Publications by authors named "Jackson Poon"
Article Synopsis
- Researchers have created a new radiopharmaceutical, PBR316, designed to target the translocator protein 18 kDa (TSPO) for studying neuroinflammation, degeneration, and cancer using PET imaging.
- PBR316 boasts high binding affinity for TSPO, improved specificity, and reduced influence from genetic variations in humans related to TSPO binding, making it a promising tool for imaging studies.
- Biodistribution studies in rats and mouse models show that PBR316 effectively accumulates in TSPO-expressing tissues, including the brain and tumors, indicating its potential for further biological and clinical research.
