Publications by authors named "Jackob Oleson"
Article Synopsis
- Cochlear implants (CIs) can help restore hearing in deaf individuals but often lead to negative outcomes due to the foreign body response (FBR), which includes immune cell infiltration and fibrosis.
- This study examines the effects of a specific drug, PLX-5622, that depletes macrophages to see if it can improve this tissue response and enhance neural health post-implantation.
- Researchers used a mouse model to measure the impact of the treatment on cochlear health and the fibrosis response after cochlear implantation, analyzing tissue samples at several time points following the procedure.
