There is an increasing need for innovative drug and prophylaxis discovery against malaria. The aim of the present study was to test antiplasmodial activity of H. (Euphorbiaceae) stem bark extracts from Kenyan folkloric medicine.
View Article and Find Full Text PDFIn Kenya, leaves and roots from Croton macrostachyus are used as a traditional medicine for infectious diseases such as typhoid and measles, but reports on possible antimicrobial activity of stem bark do not exist. In this study, the antibacterial and antifungal effects of methanol, ethyl acetate and butanol extracts, and purified lupeol of C. macrostachyus stem bark were determined against important human gram-negative pathogens Escherichia coli, Salmonella typhi, Klebsiella pneumoniae, and Enterobacter aerogenes, gram-positive Listeria monocytogenes, and a fungus Candida albicans.
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