Comparison of methods of alert acknowledgement by critical care clinicians in the ICU setting.

Background: Electronic Health Record (EHR)-based sepsis alert systems have failed to demonstrate improvements in clinically meaningful endpoints. However, the effect of implementation barriers on the success of new sepsis alert systems is rarely explored.

Objective: To test the hypothesis time to severe sepsis alert acknowledgement by critical care clinicians in the ICU setting would be reduced using an EHR-based alert acknowledgement system compared to a text paging-based system.

Laryngeal cryptococcosis: Literature review and guidelines for laser ablation of fungal lesions.

Objectives/hypothesis: To describe the demographics, clinical manifestations, diagnosis, treatment, and outcomes of laryngeal cryptococcosis. Antifungal therapy guidelines are provided and the use of laser ablation is discussed.

Data Sources: PubMed, OVID MEDLINE, and Embase databases and one patient who presented to our institution's otolaryngology department.