Publications by authors named "Jack P Guccione"
Article Synopsis
- The study examines the pathology and tissue involvement of the Monkeypox virus (MPXV) in severely ill or deceased patients, emphasizing its impact on immunocompromised individuals.
- Researchers analyzed samples from 22 patients, finding extensive viral presence in tissues, including lesions in the digestive tract and lungs, along with various complications like necrosis and bronchopneumonia.
- The findings highlight the prevalence of coinfections, the severe implications for treatment, and the need for improved biosafety protocols in medical settings dealing with mpox cases.
Article Synopsis
- The study focuses on the identification of haemophagocytosis in bone marrow and lymph nodes of patients who died from severe COVID-19, revealing it as a common finding in autopsy results.
- Autopsy specimens from patients who tested positive for SARS-CoV-2 were examined, with findings showing haemophagocytic patterns in 36% of bone marrow samples, linked to prolonged hospital stays and certain blood parameters.
- Results indicate that while few patients met the full criteria for haemophagocytic lymphohistiocytosis (HLH), the presence of haemophagocytic macrophages suggests a broader inflammatory response rather than definitive HLH.
Atypical Presentations of Collagenous Gastritis Mimicking Celiac Sprue.
Case Rep Gastrointest Med
February 2023
Collagenous gastritis has been reported as a rare cause of nausea, diarrhea, weight changes, and early satiety in female patients. Here, we describe two women aged 43 and 71 years who presented with similar symptoms. Gastric biopsies from both individuals showed thickened, irregular subepithelial collagen bands (>10 m).
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