Publications by authors named "Jack Jiang"

Objective: This paper aimed to create a voice type component profile (VTCP) to model a glottal gap during phonation.

Methods: VTCP was generated from phonation from eight excised canine larynges with induced posterior glottal gaps. Glottal gaps were induced using metal shims with widths ranging from 0.

View Article and Find Full Text PDF

Objective: The objective of this study is to expand on a novel method for semioccluded vocal tract therapy (SOVT) called controlled supraglottic pressure phonation, and investigate the mechanism that introduced supraglottic pressure mediates a decrease in impedance during SOVT therapy. Instead of the previously used CPAP mask, this study analyzes controlled supraglottic pressure phonation by use of a straw mouthpiece to deliver supraglottic pressure.

Methods: Twenty-six human subjects were randomly assigned to one of four supraglottic pressure levels: 0, 2, 4, and 6 cm HO, which were controlled through a continuous positive airway pressure device.

View Article and Find Full Text PDF

Introduction: Benign and malignant vocal fold lesions (VFLs) are growths that occur on the vocal folds. However, the treatments for these two types of lesions differ significantly. Therefore, it is imperative to use a multidisciplinary approach to properly recognize suspicious lesions.

View Article and Find Full Text PDF

Objective: Airway glottic insufficiency, or glottal gap, may lead to a breathy voice quality. It is hypothesized that a glottal gap may be a source of nonlinearity in speech production. This study aims to gain a chaotic and acoustic profile of glottal gap voice provided by phonation of excised larynges subjected to the insertion of a metal shim in the posterior glottis.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate how effective nonlinear dynamic analysis measures are in diagnosing voices with normal, benign, and malignant disorders, while also seeing how these measures correlate with perceptual ratings of voice severity.
  • Various metrics were assessed, including Jitter%, Shimmer%, and nonlinear dynamics like NEDR and ROD, with results showing that most metrics could differentiate voice disorders, although SCR struggled to distinguish benign from malignant cases.
  • The findings suggest that while both perturbation and nonlinear dynamic analyses are useful, NEDR and ROD may be particularly effective in identifying severe voice disorders, making them valuable tools in clinical practice.
View Article and Find Full Text PDF
Article Synopsis
  • Arytenoid cartilage dislocation is a rare laryngeal injury often treated with closed reduction, but methods and outcomes vary among patients.
  • This study examined the effectiveness of modified versus traditional laryngeal forceps in treating 28 patients who experienced arytenoid dislocation from endotracheal intubation, based on several evaluation techniques.
  • Results showed no significant difference in overall treatment outcomes, but the modified laryngeal forceps group had a faster recovery of normal voice, taking an average of 17.92 days compared to 31.08 days for the traditional group.
View Article and Find Full Text PDF

Background: The efficacy of inhalation therapy depends on the drug deposition in the human respiratory tract. This study investigates the effects of vocal fold adduction on the particle deposition in the glottis.

Methods: A realistic mouth-throat (MT) geometry was built based on CT images of a healthy adult (MT-A).

View Article and Find Full Text PDF

Objective: To analyze vocal fold vibration onset in patients with adductor laryngeal dystonia (ADLD) by analyzing vocal vibration opening onset position (VVOOP).

Study Design: Case-control study SETTING: A voice center.

Methods: Eleven patients with ADLD diagnosed in our voice center were enrolled in the ADLD group.

View Article and Find Full Text PDF
Article Synopsis
  • Telepractice for voice health care is gaining popularity, yet most evaluations remain in-person due to limitations in acoustic analysis methods.
  • A study was conducted with 18 female teachers with voice disorders, comparing traditional in-person voice samples with those collected via their smartphones.
  • Results suggest the voice type component (VTC) technique may provide reliable acoustic analysis from smartphone samples, offering a cost-effective solution that can improve access to voice specialists.
View Article and Find Full Text PDF

Objective: To evaluate the concept and efficacy of an adjustable implant (Prototype SH30: porcine implant and APrevent® VOIS: human concept) for treatment of unilateral vocal fold paralysis (UVFP) via in vivo mini-pig studies, human computed tomographic (CT) and magnetic resonance (MR) image analysis, ex-vivo aerodynamic and acoustic analysis.

Methods: Feasibility testing and prototype implantation were performed using in-vivo UVFP porcine model ( = 8), followed by a dimensional finding study using CT and MR scans of larynges ( = 75) for modification of the implant prototypes. Acoustic and aerodynamic measurements were recorded on excised canine ( = 7) larynges with simulated UVFP before and after medialization with VOIS-Implant.

View Article and Find Full Text PDF

Objective: The objective of this study is to introduce a novel method for semi-occluded vocal tract (SOVT) therapy called "controlled supraglottic pressure phonation," determine the mechanism by which supraglottic pressure contributes to lowering impedance during SOVT therapy, and provide the optimal supraglottic pressure range for SOVT exercises.

Methods: Twenty-five human subjects were assigned to one of five supraglottic pressure levels, 0, 2, 4, 6, and 8 cmH2O, which were controlled through a continuous positive airway pressure device. Subjects were asked to phonate during both a short- and long-duration task, in which vocal properties were measured before and after.

View Article and Find Full Text PDF

Objective: Dysphonia is very common worldwide and aerosol drug inhalation is an important treatment for patients with dysphonia. This study aimed to explore the effects of vocal fold (VF) lesions on the particle deposition pattern using computational modeling.

Methods: A realistic mouth-throat (MT) model of a healthy adult was constructed based on computed tomography images.

View Article and Find Full Text PDF

Objectives: The compound betamethasone is widely used to prevent scarring in dermatology. This study aims to explore the effects of compound betamethasone on vocal fold (VF) wound healing.

Study Design: Prospective animal study in rabbits.

View Article and Find Full Text PDF

Objective: Photodynamic therapy (PDT) is a minimally invasive method with strong tissue selectivity and nonthermal effects. We aim to investigate the efficacy of an in-office method utilizing PDT with local application of 5-aminolevulinic acid (ALA) and 635 nm diode laser for treating laryngeal leukoplakia.

Study Design: Retrospective cohort study.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate the effectiveness of an artificial intelligence (AI) system in detecting laryngeal carcinoma from vocal lesion images across multiple hospitals using different laryngoscopy systems.
  • The AI classifier achieved a sensitivity of 74.16% for identifying malignant lesions and a specificity of 78.59% for benign cases, overall demonstrating an accuracy of 78.05% in its assessments.
  • The results suggest that this AI-based diagnostic tool could enhance and standardize laryngeal cancer diagnostics for laryngologists working with various laryngoscopes.
View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the effectiveness of photodynamic therapy (PDT) in preventing vocal fold scar formation after laryngeal surgeries in rat models.
  • Laboratory techniques included vocal fold stripping, PDT application with specific laser and drug parameters, and evaluations of gene expression and tissue histology post-treatment.
  • Results indicated that PDT significantly improved vocal wound healing by enhancing healing processes and reducing scar formation, suggesting its potential as a minimally invasive treatment for vocal injuries.
View Article and Find Full Text PDF

Background: The acoustic assessment of phonation after total laryngectomy is challenged by signal aperiodicity which makes frequency-based acoustic measures less reliable. This is important for patients who use esophageal voice since voice samples mostly include type III (highly aperiodic) and 4 (chaotic) signals. As such, using non-linear measures, which are better suited for aperiodic phonation, may be useful to investigate the relationship between acoustic signal characteristics and perception of esophageal voice quality.

View Article and Find Full Text PDF

We report results of low-temperature heat-capacity, magnetocaloric-effect, and neutron-diffraction measurements of TmVO, an insulator that undergoes a continuous ferroquadrupolar phase transition associated with local partially filled 4 orbitals of the thulium (Tm[Formula: see text]) ions. The ferroquadrupolar transition, a realization of Ising nematicity, can be tuned to a quantum critical point by using a magnetic field oriented along the axis of the tetragonal crystal lattice, which acts as an effective transverse field for the Ising-nematic order. In small magnetic fields, the thermal phase transition can be well described by using a semiclassical mean-field treatment of the transverse-field Ising model.

View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates how different Mandarin vowels affect acoustic measurement parameters, aiming to address the lack of consensus in the field.
  • - Conducted at Fudan University, the study included 107 normal-voiced Mandarin speakers and analyzed various acoustic measures across six Mandarin vowels.
  • - Results showed significant variations in acoustic features among vowels, highlighting that these differences are important for clinical assessments of voice quality.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to analyze the laryngeal CT and strobe laryngoscopy signs of unilateral vocal fold hypomobility (UVFHM) in patients with well-closed glottises.
  • A total of 18 subjects were examined, including 9 with UVFHM and 9 healthy controls, to measure various vocal fold parameters and assess glottic insufficiency.
  • Results indicated that patients with UVFHM had greater height differences in the vertical plane and higher reflux scores compared to the control group, with more frequent glottic insufficiency detected through laryngeal CT than strobe laryngoscopy.
View Article and Find Full Text PDF

Hypothesis/objectives: This study's objective was to develop a method to evaluate the chaotic characteristic of alaryngeal speech. The proposed method will be capable of distinguishing between normal and alaryngeal voices, including esophageal (SE) and tracheoesophageal (TE) voices. It has been previously shown that alaryngeal voices exhibit chaotic characteristics due to the aperiodicity of their signals.

View Article and Find Full Text PDF

Background: Anterior glottoplasty is a commonly used treatment for voice feminization. But it remains in dispute over whether to suture of the ligament as part of the procedure.

Objectives: This study aimed to explore the effect of inclusion of the vocal lamina propia.

View Article and Find Full Text PDF

Cold-steel has served as the gold standard modality of phonosurgery for most of its history. Surgical laser technology has revolutionized this field with its wide use of applications. Additional modalities have also been introduced such as coagulative lasers, photodynamic therapy, and cryotherapy.

View Article and Find Full Text PDF

Objectives/hypothesis: Vocal fold (VF) fibroblasts are the central target for developing new strategies for the treatment of VF scarring and fibrosis. Asiatic acid (AA) is a triterpenoid derivate with antifibrotic properties. However, the effect of AA in VF scarring is poorly understood.

View Article and Find Full Text PDF

Purpose: The purpose of this study is to explore the effectiveness of telepractice in voice intervention for female teachers in elementary schools with self-reported voice disorders.

Methods: Thirty-five female elementary school teachers with self-reported voice disorders volunteered to participate in the study. They were divided into a telepractice voice intervention group (experimental group N=18) and a face-to-face voice intervention group (control group N=17) based on their employment setting.

View Article and Find Full Text PDF