Objective: This paper aimed to create a voice type component profile (VTCP) to model a glottal gap during phonation.
Methods: VTCP was generated from phonation from eight excised canine larynges with induced posterior glottal gaps. Glottal gaps were induced using metal shims with widths ranging from 0.
Objective: The objective of this study is to expand on a novel method for semioccluded vocal tract therapy (SOVT) called controlled supraglottic pressure phonation, and investigate the mechanism that introduced supraglottic pressure mediates a decrease in impedance during SOVT therapy. Instead of the previously used CPAP mask, this study analyzes controlled supraglottic pressure phonation by use of a straw mouthpiece to deliver supraglottic pressure.
Methods: Twenty-six human subjects were randomly assigned to one of four supraglottic pressure levels: 0, 2, 4, and 6 cm HO, which were controlled through a continuous positive airway pressure device.
Introduction: Benign and malignant vocal fold lesions (VFLs) are growths that occur on the vocal folds. However, the treatments for these two types of lesions differ significantly. Therefore, it is imperative to use a multidisciplinary approach to properly recognize suspicious lesions.
View Article and Find Full Text PDFObjective: Airway glottic insufficiency, or glottal gap, may lead to a breathy voice quality. It is hypothesized that a glottal gap may be a source of nonlinearity in speech production. This study aims to gain a chaotic and acoustic profile of glottal gap voice provided by phonation of excised larynges subjected to the insertion of a metal shim in the posterior glottis.
View Article and Find Full Text PDFBackground: The efficacy of inhalation therapy depends on the drug deposition in the human respiratory tract. This study investigates the effects of vocal fold adduction on the particle deposition in the glottis.
Methods: A realistic mouth-throat (MT) geometry was built based on CT images of a healthy adult (MT-A).
Objective: To analyze vocal fold vibration onset in patients with adductor laryngeal dystonia (ADLD) by analyzing vocal vibration opening onset position (VVOOP).
Study Design: Case-control study SETTING: A voice center.
Methods: Eleven patients with ADLD diagnosed in our voice center were enrolled in the ADLD group.
Laryngoscope Investig Otolaryngol
June 2023
Objective: To evaluate the concept and efficacy of an adjustable implant (Prototype SH30: porcine implant and APrevent® VOIS: human concept) for treatment of unilateral vocal fold paralysis (UVFP) via in vivo mini-pig studies, human computed tomographic (CT) and magnetic resonance (MR) image analysis, ex-vivo aerodynamic and acoustic analysis.
Methods: Feasibility testing and prototype implantation were performed using in-vivo UVFP porcine model ( = 8), followed by a dimensional finding study using CT and MR scans of larynges ( = 75) for modification of the implant prototypes. Acoustic and aerodynamic measurements were recorded on excised canine ( = 7) larynges with simulated UVFP before and after medialization with VOIS-Implant.
Objective: The objective of this study is to introduce a novel method for semi-occluded vocal tract (SOVT) therapy called "controlled supraglottic pressure phonation," determine the mechanism by which supraglottic pressure contributes to lowering impedance during SOVT therapy, and provide the optimal supraglottic pressure range for SOVT exercises.
Methods: Twenty-five human subjects were assigned to one of five supraglottic pressure levels, 0, 2, 4, 6, and 8 cmH2O, which were controlled through a continuous positive airway pressure device. Subjects were asked to phonate during both a short- and long-duration task, in which vocal properties were measured before and after.
Auris Nasus Larynx
February 2024
Objective: Dysphonia is very common worldwide and aerosol drug inhalation is an important treatment for patients with dysphonia. This study aimed to explore the effects of vocal fold (VF) lesions on the particle deposition pattern using computational modeling.
Methods: A realistic mouth-throat (MT) model of a healthy adult was constructed based on computed tomography images.
Laryngoscope Investig Otolaryngol
April 2023
Objectives: The compound betamethasone is widely used to prevent scarring in dermatology. This study aims to explore the effects of compound betamethasone on vocal fold (VF) wound healing.
Study Design: Prospective animal study in rabbits.
Objective: Photodynamic therapy (PDT) is a minimally invasive method with strong tissue selectivity and nonthermal effects. We aim to investigate the efficacy of an in-office method utilizing PDT with local application of 5-aminolevulinic acid (ALA) and 635 nm diode laser for treating laryngeal leukoplakia.
Study Design: Retrospective cohort study.
Background: The acoustic assessment of phonation after total laryngectomy is challenged by signal aperiodicity which makes frequency-based acoustic measures less reliable. This is important for patients who use esophageal voice since voice samples mostly include type III (highly aperiodic) and 4 (chaotic) signals. As such, using non-linear measures, which are better suited for aperiodic phonation, may be useful to investigate the relationship between acoustic signal characteristics and perception of esophageal voice quality.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
July 2022
We report results of low-temperature heat-capacity, magnetocaloric-effect, and neutron-diffraction measurements of TmVO, an insulator that undergoes a continuous ferroquadrupolar phase transition associated with local partially filled 4 orbitals of the thulium (Tm[Formula: see text]) ions. The ferroquadrupolar transition, a realization of Ising nematicity, can be tuned to a quantum critical point by using a magnetic field oriented along the axis of the tetragonal crystal lattice, which acts as an effective transverse field for the Ising-nematic order. In small magnetic fields, the thermal phase transition can be well described by using a semiclassical mean-field treatment of the transverse-field Ising model.
View Article and Find Full Text PDFHypothesis/objectives: This study's objective was to develop a method to evaluate the chaotic characteristic of alaryngeal speech. The proposed method will be capable of distinguishing between normal and alaryngeal voices, including esophageal (SE) and tracheoesophageal (TE) voices. It has been previously shown that alaryngeal voices exhibit chaotic characteristics due to the aperiodicity of their signals.
View Article and Find Full Text PDFBackground: Anterior glottoplasty is a commonly used treatment for voice feminization. But it remains in dispute over whether to suture of the ligament as part of the procedure.
Objectives: This study aimed to explore the effect of inclusion of the vocal lamina propia.
World J Otorhinolaryngol Head Neck Surg
October 2021
Cold-steel has served as the gold standard modality of phonosurgery for most of its history. Surgical laser technology has revolutionized this field with its wide use of applications. Additional modalities have also been introduced such as coagulative lasers, photodynamic therapy, and cryotherapy.
View Article and Find Full Text PDFObjectives/hypothesis: Vocal fold (VF) fibroblasts are the central target for developing new strategies for the treatment of VF scarring and fibrosis. Asiatic acid (AA) is a triterpenoid derivate with antifibrotic properties. However, the effect of AA in VF scarring is poorly understood.
View Article and Find Full Text PDFPurpose: The purpose of this study is to explore the effectiveness of telepractice in voice intervention for female teachers in elementary schools with self-reported voice disorders.
Methods: Thirty-five female elementary school teachers with self-reported voice disorders volunteered to participate in the study. They were divided into a telepractice voice intervention group (experimental group N=18) and a face-to-face voice intervention group (control group N=17) based on their employment setting.