Publications by authors named "Jack D Aylward"
Article Synopsis
- The study compares 'sawtooth' proton arc therapy (PAT) and static intensity modulated proton therapy (IMPT) in terms of their deliverability at a clinical facility.
- It evaluates various PAT plans on different types of targets, including abdominal and brain cases, using both step-and-shoot and continuous delivery methods.
- Results indicate that continuous PAT takes significantly longer in delivery time compared to static IMPT, and while the emulator can model PAT, it shows no evident advantage in beam-on time versus static IMPT, needing further validation.
Treatments at ultra-high dose rate (UHDR) have the potential to improve the therapeutic index of radiation therapy (RT) by sparing normal tissues compared to conventional dose rate irradiations. Insufficient and inconsistent reporting in physics and dosimetry of preclinical and translational studies may have contributed to a reproducibility crisis of radiobiological data in the field. Consequently, the development of a common terminology, as well as common recording, reporting, dosimetry, and metrology standards is required.
View Article and Find Full Text PDFIntroduction: The magnetic resonance linear accelerator (MRL) offers improved soft tissue visualization to guide daily adaptive radiotherapy treatment. This manuscript aims to report initial experience using a 1.5 T MRL in the first 6 months of operation, including training, workflows, timings and dosimetric accuracy.
View Article and Find Full Text PDF