Publications by authors named "Jack Coupart"
Article Synopsis
- This study focuses on understanding how mRNA-based vaccines, specifically mRNA-1273, generate immune responses by examining the antibody epitope profiles in response to the SARS-CoV-2 spike protein.
- Researchers analyzed serum samples from clinical trial participants who received the mRNA-1273 vaccine, both after the primary series and following a booster dose, to identify specific antibody responses.
- Findings revealed that while initial antibody signals decreased over time, they significantly increased again after a booster, and certain booster formulations, like variant-updated vaccines, resulted in stronger antibody responses compared to the original mRNA-1273 booster.
