Publications by authors named "Jack Considine"
Introduction: COVID-19-associated cystitis (CAC) may arise following a COVID-19 infection and is characterized by the development of novel or worsening overactive bladder (OAB). CAC is possibly associated with bladder mucosal damage and the release of pro-inflammatory cytokines, resulting in inflammation and fibrosis of the bladder wall. Amniotic membrane (AM) has been shown to possess anti-inflammatory and anti-fibrotic properties and might potentially be beneficial for CAC.
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- The study investigated the effects of injecting micronized amnion/chorion bilayer into the bladder of patients with refractory interstitial cystitis/bladder pain syndrome (IC/BPS) after traditional treatments failed.
- All fifteen patients experienced significant improvement in their symptoms one month after the injections, and this relief continued for up to six months with no adverse events reported.
- These results suggest that the amnion/chorion bilayer treatment is effective and safe for managing IC/BPS, providing hope for better long-term outcomes in affected patients.
Introduction: Interstitial cystitis/bladder pain syndrome (IC/BPS) is characterized by chronic pelvic pain and usually accompanies lower urinary tract symptoms. We have previously reported that amniotic bladder therapy (ABT) provides symptomatic improvement in refractory IC/BPS patients for up to 3 months. Herein, we evaluated the durability of ABT up to 6 months.
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