Publications by authors named "Jacira R Campos"
Article Synopsis
- The Oncofertility Consortium is an international initiative focused on addressing the reproductive concerns of cancer patients, individuals transitioning genders, and others facing treatments that may affect fertility.
- The consortium operates as a community of practice, sharing knowledge and strategies among specialists from various fields to improve healthcare outcomes and quality of life for patients.
- Their ongoing mission is to combine scientific advancements with patient needs, aiming to create a supportive network that adapts to future challenges in reproductive health and survivorship.
The quality of oocytes depends on interactions with surrounding granulosa cells. Granulosa cells are essential in normal follicular maturation process since they produce steroidal hormones and growth factors, and they play a crucial role in follicular atresia. The success in reproductive biology and medicine depends on reliable assessment of oocyte and embryo viability which presently mainly bases on oocyte and embryo morphology.
View Article and Find Full Text PDFCulture systems are available for human granulosa cells (GCs) that perpetuate luteinization. The present study examines the plating density effects and long-term serum-free culture on the in vitro dynamics differentiation of luteinizing human GCs. Cells were cultured in serum-free α-minimum essential medium (α-MEM) or serum-based tissue culture medium (TCM).
View Article and Find Full Text PDFMalignant and cardiovascular diseases are the main causes of death in Brazil. Estimates for 2013 predict the occurrence of 189,150 new cases of cancer in Brazilian women. With advanced detection tools, patients are diagnosed and treated for cancer at a younger age and are more likely to survive.
View Article and Find Full Text PDFWith the evolution of the treatment of malignant neoplasms, the survival rates of patients undergoing chemo- or radiotherapy are increasing. The continuous development of techniques of assisted human reproduction has led to important strategies in an attempt to maintain reproductive function in patients subjected to treatment of neoplastic diseases, among them cryopreservation of embryos, gametes, and ovarian cortical tissue. The freezing of ovarian tissue is currently being proposed with the primary purpose of preserving ovarian function in these patients.
View Article and Find Full Text PDFObjective: To determine the effect of storage duration on cryopreserved ovarian tissue using fresh and frozen-thawed samples.
Methods: Seventeen fertile patients underwent an ovarian biopsy during elective laparoscopic tubal ligation. The tissue sample was divided into three parts: one part was processed fresh (FG), and two were slowly frozen, cryopreserved for 30 (G30) or 180 days (G180), thawed and analyzed.