Publications by authors named "Jacek Rynkowski"

α, β, γ, and δ polymorphs of 4.6-4.8 eV wide band gap GaO photocatalysts were prepared via a soft chemistry route.

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Introduction: Environmental exposure to tobacco smoke is a significant threat for human health, where the higher is its degree, the more immature the human organism is. Therefore, the exposure to Tobacco smoke in foetal life exerts unfavourable effects on developing foetus and may cause early and distant results in children.

Material And Methods: The study comprised 318 children in their first four years of life, treated for various medical conditions.

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The degradation of sodium -cumenesulfonate (SCS) by electrochemical, photochemical, and photoelectrochemical methods in aqueous solution of NaClO, NaCl, and NaClO has been studied. It was found that as a result of NaClO electroreduction and photodecomposition, the ions Cl and ClO are formed. These ions undergo transformations into radicals, mainly Cl, Cl, ClO, ClO, and ClO, due to electrochemical and photochemical reactions.

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Homocysteine is an amino acid, which plays several important roles in human physiology. A wide range of disorders, including neuropsychiatric disorders and autism, are associated with increased homocysteine levels in biological fluids. Various B vitamins: B6 (pyridoxine), B12 (cobalamin), and B9 (folic acid) are required as co-factors by the enzymes involved in homocysteine metabolism.

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Research into biomarkers of autism is a new means of medical intervention in this disease. Chromatographic techniques, especially coupled with mass spectrometry, are widely used in determination of biomarkers and assessment of effectiveness of autism therapy owing to their sensitivity and selectivity. Among the chromatographic techniques gas chromatography and liquid chromatography, especially high-performance liquid chromatography, have found application in clinical trials.

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Urinary dicarboxylic acids are an important source of information about metabolism and potential problems especially connected with energy production, intestinal dysbiosis, and nutritional individuality in autistic children. A diet rich in vitamins and macroelements is a new idea of intervention in autism. The objective of the present study was to test the hypothesis that vitamin B2, vitamin B6, and magnesium supplementation is effective in reducing the level of dicarboxylic acids in the urine of autistic children.

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Significant differences in homocysteine levels in the urine of autistic children are observed. We hypothesized that vitamin supplementation might reduce the level of urinary homocysteine. To rationalize such a hypothesis, analyses were performed using the gas chromatography/mass spectrometry method.

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Homocysteine is an amino acid which plays several important roles in human physiology and is an important biomarker for possible deficiencies of various vitamins (vitamin B₆ and B₁₂, folic acid). In this work GC-MS method was used to determine the levels of homocysteine in the urine of autistic and healthy children. The levels of homocysteine in urine samples from 34 autistic and 21 healthy children were 2.

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Background: Tryptophan is an amino acid, which is responsible for the production of serotonin in the body. Lower levels of tryptophan may play a role in pediatric disorders. In this work the urinary level of tryptophan in autistic and healthy children was compared.

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Article Synopsis
  • Research indicates that dopamine systems may play a role in autism, and measuring urinary homovanillic acid (HVA) and vanillylmandelic acid (VMA) can provide insights into this relationship.
  • Urine samples from 20 autistic children and 36 neurologically normal children were tested, revealing higher levels of HVA and VMA in the autistic group than in healthy peers.
  • The study proposes an efficient method for analyzing urine to detect these compounds, which could be valuable for understanding dopamine-related dysfunction in autism spectrum disorders.
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