Acute lumen overdilation improves outcome after brachytherapy of in-stent restenosis.

Background: The aim of our study was to test the impact of acute lumen overdilation on neointimal hyperplasia and late lumen size after vascular brachytherapy for in-stent restenosis (ISR).

Methods: Forty-seven ISR lesions located in 47 coronary arteries in 44 consecutive patients underwent beta brachytherapy with serial intravascular ultrasound studies. Vessel, lumen, and stent cross-sectional area were measured at 1-mm steps.

Optimization of dose prescription protocol and its impact on delivered dose and vascular response after beta-radiation for in-stent restenosis. A randomized trial with serial volumetric intravascular ultrasound and dose volume histograms.

Aim: The incidence of restenosis within stented segment after intravascular brachytherapy with recommended dose prescription protocols is up to 25%. Therefore, we designed a randomized trial comparing recommended dose prescription protocol with dosing adjusted for the source-to-target distance.

Methods: Fifty-one in-stent restenosis (ISR) lesions in 48 patients underwent centered source beta-irradiation with serial intravascular ultrasound.

Determinants of model of renarrowing after beta radiation for in-stent restenosis.

Unlabelled: It is unknown whether model of renarrowing after beta-radiation for in-stent restenosis (ISR) is influenced by the type of geographic miss (GM).

Methods: In 166 ISR treated with Galileo, serial quantitative coronary angiographic analysis was done. Minimal lumen diameters and lengths were measured for (1) stent, (2) peri-stent subsegments subjected to angioplasty with/without irradiation, and (3) irradiation margins.

Angiographic restenosis following intravascular beta-brachytherapy does not correlate with delivered dose: a study with dose volume histograms. Recurrence of in-stent restenosis after brachytherapy.

Introduction: Vascular brachytherapy reduces recurrence after treatment of in-stent restenosis. However, there are still failures. The aims of the study were to investigate the relationship between two distinct dose prescriptions and the calculated dose delivered versus binary angiographic restenosis.