Crystal structure of idelalisib -butanol monosolvate dihydrate.

In the title structure, 5-fluoro-3-phenyl-2-[(1)-1-(9-purin-6-yl-amino)-prop-yl]quinazolin-4(3)-one (= idelalisib) -butanol monosolvate dihydrate, CHFNO·CHO·2HO, the idelalisib mol-ecule displays planar quinazoline and purine systems which are nearly perpendicular to one another. Seven distinct hydrogen-bonding inter-actions link the idelalisib, -BuOH and water mol-ecules into a complex chain structure with the topology of a 2,3,4,5-connected 4-nodal net having the point symbol (3.4.