Breast Cancer Plasticity after Chemotherapy Highlights the Need for Re-Evaluation of Subtyping in Residual Cancer and Metastatic Tissues.

This research paper presents a novel approach to identifying biomarkers that can be used to prognosticate patients with triple-negative breast cancer (TNBC) eligible for neoadjuvant therapy. The study utilized survival and RNA sequencing data from a cohort of TNBC patients and identified 276 genes whose expression was related to survival in such patients. The gene expression data were then used to classify patients into two major groups based on the presence or absence of Wingless/Integrated-pathway (Wnt-pathway) and mesenchymal (Mes) markers (Wnt/Mes).

Character of abuse towards the elderly through history.

Abuse, neglect and other forms of discrimination towards the elderly have always been present in history. There has been a model of "old person" in every culture, according to which older people are treated. The more idealized the model is, the less tolerant and more demanding society is towards the elderly.

[The functional ability and efficiency of motor skills evaluation of individuals admitted into nursing homes in Poland].

The objective of the study was to evaluate the functional ability and efficiency of motor skills of Individuals admitted into nursing homes. The study took place between the years of 1997-2004 in a group of 122 individuals. The evaluation was based on two scales: ADL and IADL.