Publications by authors named "Jabson Herber Profiro de Oliveira"
Why do few drug delivery systems to combat neglected tropical diseases reach the market? An analysis from the technology's stages.
Expert Opin Ther Pat
January 2022
Introduction: Many drugs used to combat schistosomiasis, Chagas disease, and leishmaniasis (SCL) have clinical limitations such as: high toxicity to the liver, kidneys and spleen; reproductive, gastrointestinal, and heart disorders; teratogenicity. In this sense, drug delivery systems (DDSs) have been described in the literature as a viable option for overcoming the limitations of these drugs. An analysis of the level of development (TRL) of patents can help in determine the steps that must be taken for promising technologies to reach the market.
View Article and Find Full Text PDFPurpose: The aim of the study was to compare the different parameters, regarding the peak and mean, at different phonatory tasks for standardization of electromyography signal of electrical activity (EA) of the laryngeal extrinsic muscles on voice evaluation.
Methods: The electrical potentials of the suprahyoid (SH) and infrahyoid (IH) muscles of 35 voluntary nondysphonic subjects were evaluated using three evaluations of rest, two maneuvers to determine maximum voluntary sustained activity (MVSA), and usual and strong intensity of vowel /ɛ/ and 20-30 count emissions. The EA signal was converted using root mean square in microvolts and normalized by mean and peak of each task.
Introduction: Total laryngectomy creates deglutition disorders and causes a decrease in quality of life Aim: To describe the impact of swallowing and quality of life of patients after total laryngectomy.
Method: A case series study. Patients completed a Swallowing and Quality of Life questionnaire composed of 44 questions assessing 11 domains related to quality of life (burden, eating duration, eating desire, frequency of symptoms, food selection, communication, fear, mental health, social functioning, sleep, and fatigue).