Publications by authors named "Jaber A"

Background: Robotic-assisted radical prostatectomy (RARP) is widely used as the main surgical approach to treat prostate cancer in the United States. Prostate size is often described as a factor affecting the outcomes of RARP as shown by many studies. However, these studies are limited to a small number of patients.

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Dengue fever, caused by the dengue virus and transmitted by mosquitoes, poses a significant global health threat, particularly in tropical and subtropical regions. Severe cases can manifest as dengue hemorrhagic fever (DHF) or dengue shock syndrome, leading to complications such as plasma leakage, fluid accumulation, respiratory distress, severe bleeding, and organ impairment. Among these complications, gastrointestinal (GI) bleeding is particularly concerning due to its potential to rapidly deteriorate the patient's condition.

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Introduction: A series of benzylidene derivatives of fenobam and its thio analogues (1-22) have been evaluated for their cytotoxicity against breast cancer (MCF-7, MDA-MB-231), ovarian cancer (A2780, SKOV-3) and cervical cancer (HELA) cell lines.

Method: These compounds (1-22) exhibited 72-83% inhibition of Erk activity against the ovarian cancer cell line (A2780). Compounds 3 and 20 showed the highest DNA damage effect in Comet Assay against the A2780 cancer cell line as compared to the other tested analogues (4, 8, 11, 12, and 13) by using % Tail DNA and OTM.

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The COVID-19 epidemic has had a significant worldwide impact, requiring measures such as quarantine, social isolation, and the closing down of educational institutions, increasing concerns about student safety. This study evaluated the mental health and sleep status of 201 college students in the UAE after the epidemic. The sample consisted primarily of females (72.

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Aims: This study aimed at the synthesis of several spiro[benzofuran-3,3'-pyrroles] derivatives by a three-component reaction conducted by mixing DMAD, N-bridgehead het-erocycles, and benzofuran-2,3-diones in dichloromethane at room temperature for 24 h. Moreover, in vitro evaluation of their cytotoxicity affinities against FMS-like tyrosine kinase 3 was carried out.

Objectives: The objective of this study was to use a one-pot, three-component reaction to synthesize a novel set of spiro[benzofuran-3,3'-pyrroles] derivatives.

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Background: The study of over the counter (OTC) vending machines is crucial given their growing popularity and potential impact on the pharmaceutical industry and consumer behaviour.

Objectives: This study involves a bibliometric quantitative analysis of academic literature to evaluate OTC vending machines in terms of their evolution, current trends, and potential areas for future research

Methods And Materials: The Scopus database was searched using its advanced search tool, focusing on papers that included the search query in their titles, abstracts, and keywords. Data analysis included bibliometric indicators such as publication counts, citation trends, and co-authorship networks, which were visualized using VOSviewer software (version 1.

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Article Synopsis
  • The article DOI: 10.1371/journal.pone.0273209 has been corrected to address previous inaccuracies.
  • The corrections may involve changes in data, findings, or conclusions presented in the original publication.
  • Readers are encouraged to refer to the updated version for the most accurate and reliable information.
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Introduction: Prostate cancer remains a significant health concern, with radical prostatectomy being a common treatment approach. However, predicting postoperative functional outcomes, particularly urinary continence and erectile function, poses challenges. Emerging artificial intelligence (AI) technologies offer promise in predictive modeling.

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Probing the chemical profiles and biological activities of medicinal plants is important for the discovery of new potent therapeutic products. Our study deciphers the chemical composition of the essential oils (EOs) obtained from three different flowers of and evaluates their antioxidant and anticancer activities. This work represents the first study of EOs obtained from this plant and is based particularly on the difference in flower color.

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Article Synopsis
  • * Recent advancements include the approval of the first gene therapy using a recombinant adeno-associated vector (rAAV) to deliver a microdystrophin, but significant therapeutic challenges remain.
  • * Major issues include potential immunotoxicity and hepatotoxicity from high doses of rAAV, as well as functional limitations and immunological risks associated with microdystrophin, prompting further exploration for improved treatment options.
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Article Synopsis
  • * Conducted with 186 participants at Jordan University Hospital, the study included translations, cultural adaptations, and various validations of the questionnaire, finding acceptable internal consistency except in one domain.
  • * Results revealed correlations between OSA-18 scores and the Pediatric Sleep Questionnaire, but not with the Apnea-Hypopnea Index, prompting further research into better diagnostic tools for OSA in similar populations.
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Background Pressure ulcers are significant health issues affecting elderly patients, leading to severe complications, prolonged hospital stays, and high healthcare costs. Preventive care by home caregivers plays a crucial role in mitigating the development of pressure ulcers. Objective This study aims to assess home caregivers' knowledge of pressure ulcer prevention and investigate the factors associated with knowledge levels in elderly patients in Al Ahsa, Saudi Arabia.

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Background: Extremely obese patients can benefit greatly from bariatric surgery, a common and successful therapeutic procedure for treating obesity and accompanying medical issues. Although sleeve gastrectomy and gastric bypass have already demonstrated their effectiveness in this demographic, long-term results were not stated in the literature. The purpose of this research is to examine the long-term outcomes of sleeve gastrointestinal surgery and gastric bypass.

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Carbon pricing is a key component of current climate policy agendas. There are a variety of societal and health impacts from carbon pricing interventions (e.g.

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Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening condition that can lead to severe morbidity and mortality if untreated. This case report discusses a 31-year-old male with dengue fever who developed TTP, resulting in fatality despite timely diagnosis and comprehensive treatment. The patient presented with worsening symptoms, including body aches, gastrointestinal bleeding, and neurological issues.

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The advent of precision diagnostics in pediatric dentistry is shifting towards ensuring early detection of dental diseases, a critical factor in safeguarding the oral health of the younger population. In this study, an innovative approach is introduced, wherein Discrete Wavelet Transform (DWT) and Generative Adversarial Networks (GANs) are synergized within an Image Data Fusion (IDF) framework to enhance the accuracy of dental disease diagnosis through dental diagnostic systems. Dental panoramic radiographs from pediatric patients were utilized to demonstrate how the integration of DWT and GANs can significantly improve the informativeness of dental images.

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Unmanned aerial vehicles (UAVs) require fault diagnosis for safe operation. Here, we present a protocol for UAV fault diagnosis using signal processing and artificial intelligence. We describe steps for collecting vibration-based signal data, preprocessing, and feature extraction using a 3-axis accelerometer or similar sensors.

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Background: Kidney function assessment is crucial in critical illness patients and is required before administering renally excreted medication, especially antibiotics and antiepileptics. Conventional clinical practice often focuses on renal impairment with low creatinine clearance (CrCl) and overlooks the augmented renal clearance (ARC), which is defined by (CrCl) more than 130 ml/min. This typical demonstration neglects individuals who experience hyperfunctioning kidneys.

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Duchenne Muscular dystrophy (DMD), a yet-incurable X-linked recessive disorder that results in muscle wasting and loss of ambulation is due to mutations in the dystrophin gene. Exonic duplications of dystrophin gene are a common type of mutations found in DMD patients. In this study, we utilized a single guide RNA CRISPR strategy targeting intronic regions to delete the extra duplicated regions in patient myogenic cells carrying duplication of exon 2, exons 2-9, and exons 8-9 in the DMD gene.

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Design: This retrospective cohort study aimed to investigate the risk and variables of tooth loss for teeth adjacent to dental implants compared to teeth nonadjacent to implants. The study followed the STROBE guidelines and was approved by the Institutional Review Board.

Cohort Selection: The study included patients treated with dental implants at UCSF School of Dentistry between 2000 and 2020.

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Fault detection and isolation in unmanned aerial vehicle (UAV) propellers are critical for operational safety and efficiency. Most existing fault diagnosis techniques rely basically on traditional statistical-based methods that necessitate better approaches. This study explores the application of untraditional feature extraction methodologies, namely Permutation Entropy (PE), Lempel-Ziv Complexity (LZC), and Teager-Kaiser Energy Operator (TKEO), on the PADRE dataset, which encapsulates various rotor fault configurations.

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Background: Lower urinary tract symptoms are common and can significantly impact quality of life, especially in men with co-morbidities and end-stage renal disease. The presence of lower urinary tract symptoms affect the quality of life of patients on hemodialysis.

Objectives: The purpose of this study is assessing the presence and severity of lower urinary tract symptoms among male patients on hemodialysis.

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Background: A series of novel 2-(isoquinolin-1-yl)-spiro[oxindole-3,3'-pyrrolines] were synthesized by a one-pot three-component reaction involving dimethyl acetylenedicarboxylate, 3-phenylimidazo[5,1-a]isoquinoline and N-alkylisatins in chloroform at ∼60°C for 24 h.

Aims: This study aimed at the synthesis of novel spirooxindole-3,3'-pyrrolines derivatives and in vitro evaluation of cytotoxicity affinities in cross-correlations with their anti-inflammation and radical scavenging capacities.

Objectives: The objective of this study was to use a one-pot, three-component reaction to synthesize a novel set of spirooxindole-3,3'-pyrrolines derivatives.

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Purpose: Vaccination against HPV plays a crucial role in preventing cervical cancer and related health issues. This study aimed to (1) assess knowledge, awareness, intentions, and attitudes regarding HPV and vaccination among Jordanian parents, and (2) evaluate the efficacy of two intervention strategies in promoting knowledge, awareness, and attitudes towards HPV vaccinations.

Methods: In study one, a web-based survey was used to collect data from Jordanian parents.

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: There is a lack of evidence regarding the impact of time loss, match exposure, and age at injury on career progression in elite football. Therefore, the aim of this study was to identify injury characteristics and their influence on career progression in a German youth academy. : During the 2012/2013 season, a prospective cohort study reported 107 time-loss injuries among 130 young athletes from an elite German soccer academy.

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