The structural, electronic, optical, thermoelectric, and magnetic properties of the Perovskite PrFeO: DFT and Monte Carlo simulations.

Context: Nowadays, Perovskite materials with diverse compositions and structures have garnered significant attention for their potential applications across various industrial and technological fields. Here, we investigated the structural, electronic, optical, thermodynamic, thermoelectric, and magnetic properties of perovskite PrFeO using density functional theory and Monte Carlo simulations. The optimization results demonstrate that the ferromagnetic phase is more stable than the antiferromagnetic phase.

Investigation into the physical characteristics of the compounds XBiSe (X = Li, Na or K).

Context: As new materials, the ternary chalcogenides have recently brought scientists' attention. These materials are a novel class of semiconducting chemical compounds. They allow the increase of the photo-conversion efficiency, the performance, and the cheap energy cost.

A vast dataset for Kurdish handwritten digits and isolated characters recognition.

This article presents two massive datasets for central Kurdish handwriting digits and isolated characters named and . The first dataset, named dataset, contains 70,000 images of Kurdish digits, 7000 images for each digit, and a printed A4 paper with a grid of 10 × 10 is used for data collection. Apart from digits, the dataset includes 245,000 images of all Kurdish characters, 7000 images for each character; data was collected via a printed A4 paper with a grid of 12 × 10 for this dataset.

Matching study using health and police datasets for characterising interpersonal violence in the community of Khayelitsha, South Africa 2013-2015.

Objectives: The Cardiff Model of data sharing for violence prevention is premised on the idea that the majority of injury cases presenting at health facilities as a result of interpersonal violence will not be reported to the police. The aim of this study was to determine the concordance between violent crimes reported to the police with violence-related injuries presenting at health facilities in Cape Town, South Africa.

Methods: We conducted a retrospective analysis of secondary cross-sectional health and police data, from three health facilities and three police stations in the community of Khayelitsha, Cape Town.

Electronic, magnetic, elastic, thermal and thermoelectric proprieties of CoMnZ (Z=Al, Ge, Sn).

The full-potential linearized augmented plane-wave (FLAPW) method, which is based on density functional theory using the "WIEN2k" code. The exchange-correlation functional was taken within the generalized gradient approximation (GGA), has been used to study the structural, electronic, mechanical, magnetic, and thermal properties of CoMnZ (Z = Al, Ge, Sn) (CMZ) alloy. When using the GGA + U approximation, all compounds depict half-metallic behavior due to spin polarization at the Fermi level.

Study of the Optical and Thermoplasmonics Properties of Gold Nanoparticle Embedded in AlO Matrix.

In this paper, the optical and thermoplasmonics properties of nanocomposites consisting of spherical gold nanoparticles (AuNPs) integrated in matrix are determined using the Finite Element Method (FEM). Firstly, the refractive index , extinction coefficient , absorption coefficient , and optical conductivity are calculated from the effective complex permittivity obtained by solving the Laplace's equation for different size and concentration of nanoparticles. The surface plasmon resonance (SPR) properties of AuNPs are optimized from the peak presented in the absorption coefficient spectrum.

Micro and nanorobot-based drug delivery: an overview.

Progress in the drug delivery system in the last few decades has led to many advancements for efficient drug delivery. Both micro and nanorobots, are regarded as superior drug delivery systems to deliver drugs efficiently by altering other forms of energy into propulsion and movements. Furthermore, it can be advantageous as it is directed to targeted sites beneath physiological environments and conditions.

Fabrication, in vitro and ex vivo evaluation of proliposomes and liposomal derived gel for enhanced solubility and permeability of diacerein.

The present study is associated with the development of proliposomes and liposomal derived gel for enhanced solubility and permeability of diacerein. Proliposomes were developed by thin film hydration method and converted into the liposomal derived gel using carbopol-934 as a gelling agent. Formulations with varied lecithin to cholesterol ratios were investigated to obtain the optimal size, entrapment efficiency, and enhanced in vitro dissolution.

Lipid poly (ɛ-caprolactone) hybrid nanoparticles of 5-fluorouracil for sustained release and enhanced anticancer efficacy.

Aims: The present study aimed to develop and characterize poly (ɛ-caprolactone) (PCL) based lipid polymer hybrid nanoparticles for sustained delivery and in-vitro anti-cancer activity in MCF-7 and HeLa cells cancer cell line.

Materials And Methods: The nanoprecipitation method was used for the development of 5-fluorouracil loaded lipid polymer hybrid nanoparticles (LPHNPs). The developed LPHNPs were characterized for physicochemical characteristics and the anti-cancer effect was evaluated in MCF-7 and HeLa cells.

Statistically optimized pentazocine loaded microsphere for the sustained delivery application: Formulation and characterization.

Pentazocine (PTZ) is a narcotic analgesic used to manage moderate to severe, acute and chronic pains. In this study, PTZ loaded Ethyl cellulose microsphere has been formulated for sustained release and improved bioavailability of PTZ. These microspheres were fabricated by oil in water emulsion solvent evaporation technique.

Recent Advancements in Stimuli Responsive Drug Delivery Platforms for Active and Passive Cancer Targeting.

The tumor-specific targeting of chemotherapeutic agents for specific necrosis of cancer cells without affecting the normal cells poses a great challenge for researchers and scientists. Though extensive research has been carried out to investigate chemotherapy-based targeted drug delivery, the identification of the most promising strategy capable of bypassing non-specific cytotoxicity is still a major concern. Recent advancements in the arena of onco-targeted therapies have enabled safe and effective tumor-specific localization through stimuli-responsive drug delivery systems.

In vitro anti-leukemic assessment and sustained release behaviour of cytarabine loaded biodegradable polymer based nanoparticles.

Aims: The study aimed to develop, characterize, and evaluate poly (ɛ-caprolactone) (PCL) based nanoparticles for the sustained release behaviour of cytarabine and to investigate the in vitro anti-cancer influence on KG-1 leukemic cell line.

Materials And Methods: Nanoprecipitation method was used for the preparation of cytarabine loaded PCL nanoparticles. The developed nanoparticles were characterized for physicochemical properties and the anti-leukemic effect on the KG-1 cell line was evaluated.

Effect of adding a capsule with activated charcoal to abdominal ultrasound preparation on image quality.

Patient preparation for routine abdominal ultrasound, such as fasting for 8 hours and having a light meal the night before the examination, is a common practice employed to avoid digestive motility and gases, which are considered the main causes of artifacts and image quality degradation. Patient preparation before abdominal ultrasound plays a major role to ensure better visualization of internal organs and pathologies by minimizing artifacts, but because abdominal gases are still present in many patients and in large amounts, causing artifacts, it is important to search for new, safe, efficient, reliable and cost-effective methods to improve patient preparation by eliminating excessive abdominal gases. This was a prospective study involving a randomly selected sample of 52 adult patients, both men and women, of different age groups.

Ionically Cross-Linked Chitosan Nanoparticles for Sustained Delivery of Docetaxel: Fabrication, Post-Formulation and Acute Oral Toxicity Evaluation.

Introduction: Polymeric nanoparticles are potential carriers for the efficient delivery of hydrophilic and hydrophobic drugs due to their multifaceted applications. Docetaxel is relatively less hydrophobic and twice as potent as paclitaxel. Like other taxane chemotherapeutic agents, docetaxel is not well tolerated and shows toxicity in the patients.

Diagnostic reliability of the Thyroid Imaging Reporting and Data System (TI-RADS) in routine practice.

Purpose: To evaluate the diagnostic reliability of Thyroid Imaging Reporting and Data System (TI-RADS) classifications described by American College of Radiology (ACR) and Kwak . by calculating the risk of malignancy, to assess the role of TI-RADS in reducing fine-needle aspiration cytology (FNAC) of benign lesions.

Material And Methods: This was a prospective study during the period from December 2017 to August 2018.

Is the introduction of violence and injury observatories associated with a reduction in violence-related injury in adult populations? A systematic review and meta-analysis.

Objective: The aim of this study was to summarise the results from existing studies reporting on the effectiveness of the introduction of violence and injury observatories (VIOs).

Design: This is a systematic review and meta-analysis study.

Data Sources: We searched multiple electronic databases including but not limited to PubMed, PsycINFO, SCOPUS, Cochrane Collaboration, Campbell Collaboration and Web of Knowledge.

Correction to: Effectiveness and sustainability of a structured group-based educational program (MEDIHEALTH) in improving medication adherence among Malay patients with underlying type 2 diabetes mellitus in Sarawak State of Malaysia: study protocol of a randomized controlled trial.

After publication of the original article [1], the authors have notified us that there are changes to the primary outcome of the study, instrument, subject's inclusion criteria, the funding and acknowledgements. These changes were made during the recruitment of participants and after approved by the Medical Research and Ethics Committee (MREC), National Institutes of Health Malaysia, on 16th November 2018.

Modified Delphi study to determine optimal data elements for inclusion in a pilot violence and injury observatory in Cape Town, South Africa.

Introduction: Violence and injury observatories (VIOs) are primarily a tool to aid safety and security stakeholders within both governments and non-governmental organisations to develop interventions focused on violence prevention and related to citizen safety issues. VIOs are centres that focus on collating and integrating violence-related injury data sources to monitor, evaluate, and study the progression of violence and crime in a targeted region. In preparation for implementing a pilot VIO in Cape Town, we sought to determine the optimal indicators, datasets and research priorities for inclusion.

Enhancement of Dissolution and Skin Permeability of Pentazocine by Proniosomes and Niosomal Gel.

Proniosomes (PN) are the dry water-soluble carrier systems that may enhance the oral bioavailability, stability, and topical permeability of therapeutic agents. The low solubility and low oral bioavailability due to extensive first pass metabolism make Pentazocine as an ideal candidate for oral and topical sustained release delivery. The present study was aimed to formulate the PNs by quick slurry method that are converted to niosomes (liquid dispersion) by hydration, and subsequently formulated to semisolid niosomal gel.

Rationale and design of the violence, injury and trauma observatory (VITO): the Cape Town VITO pilot studies protocol.

The establishment of violence and injury observatories elsewhere has been found to reduce the burden within a relatively short period. Currently no integrated system exists in South Africa to provide collated data on violence, to allow for targeted interventions and routine monitoring and evaluation.This research seeks to identify if bringing multiple data sources, including but not limited to data from the South African Police Service (SAPS), Forensic Pathology Services (FPS), Emergency Medical Services (EMS) and local hospital clinical databases, together are (1) feasible; (2) able to generate data for action, that is valid, reliable and robust and (3) able to lead to interventions.

Effects of aflatoxin B1 combined with ochratoxin A and/or zearalenone on metabolism, immune function, and antioxidant status in lactating dairy goats.

Objective: This experiment investigated the effects of aflatoxin B1 (AFB1) alone or mixed with ochratoxin A (OTA) and/or zearalenone (ZEA) on the metabolism, immune function, and antioxidant status of dairy goats.

Methods: Fifty lactating Laoshan dairy goats were randomly assigned to one of five treatment groups (n = 10) for 14 days. Goats were fed no additive (control) or administered with 50 μg AFB1/kg dry matter (DM) (AFB1), 50 μg AFB1/kg DM+100 μg OTA/kg DM (AFB1+ OTA), 50 μg AFB1/kg DM+500 μg ZEA/kg DM (AFB1+ZEA), or 50 μg AFB1/kg DM+100 μg OTA/kg DM+500 μg ZEA/kg DM (AFB1+OTA+ZEA).

Non-invasive strategies for targeting the posterior segment of eye.

The safe and effective treatment of eye diseases has been remained a global myth. Several advancements have been done and various drug delivery and treatment techniques have been suggested. The Posterior segment disorders are the leading cause of visual impairments and blindness.

Compliance of Community Pharmacists and Private General Medical Practitioners With Malaysian Laws on Poisons and Sale of Drugs.

Background: Compliance of community pharmacists (CPs) and private general medical practitioners (GPs) with Malaysian Laws on Poisons and Sale of Drugs is crucial in encouraging rational supply of medicine to patients that will subsequently lead to rational use of medicine, especially controlled medicine and psychotropic substances. This study aims to identify the trend of yearly compliance rate of both CPs and GPs with the Malaysian Laws on Poisons and Sale of Drugs, and to quantify the effectiveness of disciplinary actions in improving their compliance level.

Methods: This is a retrospective observation study from the Sarawak state Pharmaceutical Enforcement Division (PED) inspection reports on CPs and GPs from January 1, 2012, to December 31, 2014.