Publications by authors named "JJ Reidy"

Article Synopsis
  • Severe acute corneal hydrops was observed in a 32-year-old man with undiagnosed keratoconus, identified through anterior segment optical coherence tomography (AS-OCT) that showed a distinct tissue ridge around a break in the Descemet membrane (DM).
  • The patient initially received conservative treatment with hypertonic saline, followed by an ultrathin Descemet-stripping automated endothelial keratoplasty (UT-DSAEK), which successfully improved his vision from uncorrected 20/80.
  • The findings suggest a need for further research into the mechanisms behind endothelial keratoplasty and the implications of posterior stromal rupture in cases of acute corneal hydrops.
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: To report a series of cases demonstrating the resolution of a keratitis (AK) with adjunctive use of oral miltefosine.: Retrospective case series.: The first case was a 27-year-old female who presented with severe pain and photophobia.

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: To report a case of atypical keratitis caused by : Retrospective case review.: A 49 year-old woman of South Asian descent presented with a non-discrete corneal ulcer with a small overlying epithelial defect in the right eye. Cultures were obtained, a topical fluoroquinolone was continued, and a topical steroid was added.

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We present a case of a 49 year-old male with history of corneal neovascularization secondary to herpes zoster keratitis that clinically and subjectively improved for approximately 4 months after treatment with argon laser photocoagulation to feeder vessels and subconjunctival bevacizumab. This is the first report in the literature that describes this novel combination treatment for corneal neovascularization in the setting of varicella-zoster virus and discusses its efficacy.

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We present a study of the interplay among electric charging rate, capacitance, salt removal, and mass transport in "flow-through electrode" capacitive deionization (CDI) systems. We develop two models describing coupled transport and electro-adsorption/desorption which capture salt removal dynamics. The first model is a simplified, unsteady zero-dimensional volume-averaged model which identifies dimensionless parameters and figures of merits associated with cell performance.

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Posterior keratoconus (PKC) is a rare, typically non-inflammatory condition that is characterised by an abnormal posterior corneal curvature, which may be accompanied by overlying stromal opacification. It is usually congenital and can be associated with other ocular and systemic abnormalities. PKC remains a clinical diagnosis, although imaging techniques including ultrasound biomicroscopy and anterior segment optical coherence tomography may be useful tools for confirmation and classification.

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Optic gliomas are brain tumors characterized by slow growth, progressive loss of vision, and limited therapeutic options. Optic gliomas contain various amounts of myxoid matrix, which can represent most of the tumor mass. We sought to investigate biological function and protein structure of the myxoid matrix in optic gliomas to identify novel therapeutic targets.

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Article Synopsis
  • Toxic keratoconjunctivitis (TK) is a serious but often overlooked complication resulting from the use of eye medications or exposure to certain environments.
  • Identifying the cause requires a thorough patient history and clinical examination, with common triggers being preservatives in eye drops, topical antibiotics, and anesthetics.
  • Effective management strategies include using preservative-free options and, in severe cases, may involve topical steroids, antibiotics, or even surgery to prevent lasting eye damage.
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  • The study assesses graft dislocation rates in patients who had Descemet stripping automated endothelial keratoplasty (DSAEK) following a previous penetrating keratoplasty (PKP).
  • Out of 97 eyes, 31% experienced graft dislocation post-surgery, with the majority requiring a rebubble to reattach.
  • Risk factors identified for higher dislocation rates include donor grafts being smaller than the host and the presence of glaucoma drainage devices.
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Article Synopsis
  • The study reports on the outcomes of penetrating keratoplasty (PK) in patients with active Acanthamoeba keratitis (AK) who did not improve with medical therapy.
  • Nine patients underwent PK during the acute phase due to inadequate response to treatment, and the antiamoebic therapy was reduced post-surgery.
  • After an average of 17 months, patients demonstrated good visual acuity and symptom resolution without recurrence, indicating that PK can be an effective option for severe cases of AK.
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Background: The kidney's role in the pathogenesis of salt-induced hypertension remains unclear. However, it has been suggested that inherited morphological renal abnormalities may cause hypertension. We hypothesized that functional, not morphological, derangements in Dahl salt-sensitive rats' kidneys cause NaCl retention that leads to hypertension accompanied by renal pathologic changes and proteinuria.

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  • A case study details a patient who developed Nocardia asteroides keratitis three weeks after undergoing LASIK in a nontraumatized eye, leading to vision loss and inflammation.
  • The initial treatment with topical antibiotics failed, necessitating a penetrating keratoplasty (PKP) surgery to address the severe infection.
  • After surgery, the patient experienced a recurrence of the infection at the graft-host interface, which was successfully treated with a combination of moxifloxacin and imipenem.
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Purpose: Human corneal limbal stem cells mature and repopulate the superficial layers of the cornea throughout life. In this study, we tested the hypothesis that human corneal stem cells, derived from neural ectoderm, can exhibit functional neuronal properties.

Methods: Human corneal limbal tissue (donor age 6 weeks to 92 years) was obtained from Upstate New York Transplant Services.

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We study the Dalitz plot of the decay D(+)-->K(-)pi(+)pi(+) with a sample of 15090 events from Fermilab experiment E791. Modeling the decay amplitude as the coherent sum of known Kpi resonances and a uniform nonresonant term, we do not obtain an acceptable fit. If we allow the mass and width of the K(*)(0)(1430) to float, we obtain values consistent with those from PDG but the chi(2) per degree of freedom of the fit is still unsatisfactory.

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Penetrating keratoplasty in infants and young children is performed on an infrequent basis. The most common indication is visually significant congenital corneal opacity. Surgery must be performed early to avoid amblyopia.

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We have studied the diffractive dissociation into dijets of 500 GeV/c pions scattering coherently from carbon and platinum targets. Extrapolating to asymptotically high energies (where t(min)-->0), we find that when the per-nucleus cross section for this process is parametrized as sigma = sigma0Aalpha, alpha has values near 1.6, the exact result depending on jet transverse momentum.

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We present the first direct measurements of the pion valence-quark momentum distribution which is related to the square of the pion light-cone wave function. The measurements were carried out using data on diffractive dissociation of 500 GeV/c pi(-) into dijets from a platinum target at Fermilab experiment E791. The results show that the /q&q> light-cone asymptotic wave function describes the data well for Q2 approximately 10 (GeV/c)(2) or more.

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We report results of a search for flavor-changing neutral current (FCNC), lepton flavor, and lepton-number violating decays of the D0 (and its antiparticle) into three and four bodies. Using data from Fermilab charm hadroproduction experiment E791, we examine modes with two leptons (muons or electrons) and a rho(0), K( *0), or straight phi vector meson or a nonresonant pi(pi), Kpi, or KK pair of pseudoscalar mesons. No evidence for any of these decays is found.

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From a sample of 1172 +/- 61 D(+)-->pi(-)pi(+)pi(+) decays, we find gamma(D(+)-->pi(-)pi(+)pi(+))/gamma(D(+)-->K-pi(+)pi(+)) = 0.0311 +/- 0.0018(+0.

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From a sample of 848+/-44 D(+)(s)-->pi(-)pi(+)pi(+) decays, we find gamma(D(+)(s)-->pi(-)pi(+)pi(+))/gamma(D(+)(s)-->straight phipi(+)) = 0.245+/-0.028(+0.

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