A first-pass cost analysis of propofol versus barbiturates for children undergoing magnetic resonance imaging.

Intravenous (IV) propofol was compared with IV thiopental/pentobarbital as a sedative for children undergoing magnetic resonance imaging (MRI) of the brain or spine. Fifty-eight outpatients (aged 11 mo to 6 1/2 yr, ASA grade I and II) were enrolled in the study and randomized to two groups. After IV cannulation, Group I received IV propofol (1-2 mg/kg), followed immediately by a propofol infusion (75-100 micrograms.

Surround inhibition among projection neurons is weak or nonexistent in the rat neostriatum.

1. Antidromic activation of striatal spiny projection neurons by substantia nigra stimulation in vivo did not evoke inhibitory postsynaptic potentials (IPSPs) in the antidromically activated neurons, or in neighboring spiny neurons. 2.

Effect of human bowel wall distension on translocation of indigenous bacteria and endotoxins.

The effect of colonic distension on the translocation of indigenous bacteria and endotoxins was prospectively assessed in 50 consecutive patients undergoing colonoscopy. Semiquantitative bacteriologic cultures, chromogenic LAL testing for endotoxemia, and serial determinations of inflammatory markers were used. At the end of the endoscopic procedure, true bacteremia was found in only two patients with obstructing colorectal cancer.

Prolonged responses in rat cerebellar Purkinje cells following activation of the granule cell layer: an intracellular in vitro and in vivo investigation.

We obtained intracellular recordings of 84 Purkinje cells in vitro from guinea pig slices and of 35 cells in vivo from ketamine-anesthetized rats in order to assess detailed properties of synaptic responses in Purkinje cells following granule cell activation. In vitro, electrical stimulation of the granule cell layer underlying recorded Purkinje cells was used in sagittal slices to predominantly activate synapses on ascending granule cell axons. In vivo, stimulation of the upper lip was used to activate Purkinje cells overlying the upper lip patch in the granule cell layer of crus IIa.

Kansas risk management laws and nursing practice: approaches towards compliance in reporting substandard nursing practice in acute care facilities.

This article provides a structural outline of the many basic elements needing to be considered when institutions are developing a system for review of incidents that may fall below the applicable standard of care. Details for program development need to be explored and implemented with the mindset that the process will be modified and continuously improved over time. Protecting the interest of the individual licensee, the healthcare institution and the public are important aspects that demand attention when complying with the Kansas Risk Management Laws as they pertain to nursing practice.

Primate basal ganglia activity in a precued reaching task: preparation for movement.

Single cell activity was recorded from the primate putamen, caudate nucleus, and globus pallidus during a precued reaching movement task. Two monkeys were trained to touch one of several target knobs mounted in front of them after an LED was lighted on the correct target. A precue was presented prior to this target "go cue" by a randomly varied delay interval, giving the animals partial or complete advance information about the target for the movement task.

Latex-specific proteins causing immediate-type cutaneous, nasal, bronchial, and systemic reactions.

We examined 70 patients reporting hypersensitivity reactions caused by latex articles. All patients suffered from urticaria, 36 from rhinitis, 31 from conjunctivitis, 22 from dyspnea, and 17 from systemic reactions, and four patients developed severe systemic complications during surgery. By means of inhalative challenge tests with powdered latex gloves, it could be demonstrated that the glove powder (cornstarch) obviously functions as a carrier for latex allergens, which then become airborne.

[Exogenous allergic alveolitis caused by mouldy hazel nut leaves].

A 62-year old farmer woman from the northeastern, very rainy part of Turkey has been collecting large amounts of green and brown involucral hazel-nut leaves for subsequent use as fuel. For the last 20 years she had been complaining of cough, respiratory distress and intermittent fever. In the course of years of continual antigen exposure she developed the clinical and x-ray signs of fibrosis of the lung.

Effect of phloridzin and ouabain on cadmium and zinc absorption using an isolated perfused rat intestinal preparation.

The action of phloridzin and ouabain on Zn and Cd (as well as glucose) absorption was studied using an isolated vascularly and luminally perfused rat preparation. Phloridzin and ouabain (both at concentrations of 1 x 10(-4) M) significantly decreased glucose uptake. The addition of phloridzin (1 x 10(-4) M) to the luminal medium (LM) which contained either Cd (0.

Absorption interactions of zinc and cadmium in the isolated perfused rat intestine.

Interactions between zinc and cadmium using either 65Zn or 109Cd in separate experiments were studied using an isolated rat intestinal preparation. In all experiments, the intraluminal concentrations of Zn were 0, 5, 10 or 20 mg/L and 0, 0.03, 0.

A multiwire microelectrode for single unit recording in deep brain structures.

A method is described by which a single shaft multiwire microelectrode can be fabricated efficiently. The resulting electrode can be attached to a commercial microdrive and used for single neuronal unit recording from one or more tracks in deep brain structures of anesthetized or awake animals. The electrode consists of a 30 gauge stainless steel cannula through which multiple strands of 13 micron insulated tungsten microwires are threaded.

Cause of death in 1144 patients with diabetes mellitus: an autopsy study.

The pathological reports for all patients over 13 years of age who had had an autopsy at one of three university-affiliated hospitals between 1967 and 1976 were reviewed to determine the principal cause of death. The clinical records of the patients with diabetes were reviewed to verify the diagnosis and to determine the known duration of diabetes. There were 1144 patients with diabetes mellitus and 5674 without.