Physiological correlates of support for self-expansion and links to goal pursuit in retirement.

Partner support for self-expansion has been associated with long-term health and retirement satisfaction, yet the underlying physiological correlates are unknown. We predicted that partner support for self-expansion would be associated with short-term physiology and behavior as well as long-term goal pursuit. And 100 couples with at least one retiree within 2 years of retirement visited the laboratory and had a discussion of the retirees' future goals for retirement.

The Role of c-Met as a Biomarker and Player in Innate and Acquired Resistance in Non-Small-Cell Lung Cancer: Two New Mutations Warrant Further Studies.

The c-Met receptor is a therapeutically actionable target in non-small-cell lung cancer (NSCLC), with one approved drug and several agents in development. Most suitable biomarkers for patient selection include c-Met amplification and exon-14 skipping. Our retrospective study focused on the frequency of different c-Met aberrations (overexpression, amplification and mutations) in 153 primary, therapy-naïve resection samples and their paired metastases, from Biobank@UZA.