Publications by authors named "J-P Riveline"

Objective: To examine the efficacy and safety of the tubeless Omnipod 5 automated insulin delivery (AID) system compared with pump therapy with a continuous glucose monitor (CGM) in adults with type 1 diabetes with suboptimal glycemic outcomes.

Research Design And Methods: In this 13-week multicenter, parallel-group, randomized controlled trial performed in the U.S.

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Article Synopsis
  • Diabetes significantly increases the risk of cardiovascular diseases, particularly among individuals with type 2 diabetes (T2D), where circulating monocytes play a crucial role in inflammation related to both diabetes and atherosclerosis.* -
  • A study involving 672 T2D patients found a positive correlation between blood monocyte counts and coronary artery calcium scores, which are indicators of cardiovascular risk, revealing distinct monocyte subtypes associated with varying cardiovascular risk levels.* -
  • The research indicates that analyzing monocyte frequency and profiles can serve as valuable predictors for cardiovascular events in T2D patients, highlighting potential mitochondrial dysfunction in these individuals' immune responses.*
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  • People with type 1 diabetes who use insulin pumps often experience changes in their blood sugar levels, which may be due to how insulin spreads under their skin.
  • A new method was developed to study how insulin moves in the skin by using special imaging and measuring pressure in real-time.
  • The study found that most insulin was delivered under the skin correctly, but some errors occurred, like air bubbles forming, and this method can help improve how insulin is given in the future.
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