Researchers aimed to identify ulcerative colitis (UC) patients at risk for primary sclerosing cholangitis (PSC), as PSC impacts UC outcomes.
A retrospective study analyzed data from multiple institutions, assessing various genetic and clinical predictors to evaluate the risk of developing PSC among UC patients.
Results indicated that certain genetic markers significantly increased the risk of PSC and that the study's model showed strong accuracy, potentially aiding in early identification and management of at-risk patients.