Publications by authors named "J-M Malinovsky"
Article Synopsis
- The study investigates the differences in plasma histamine and tryptase levels in patients experiencing severe allergic reactions during anesthesia compared to those in shock from other causes.
- Researchers analyzed data from patients with confirmed allergies to administered agents and compared their mediator concentrations to patients suffering from septic or cardiogenic shock during resuscitation efforts.
- Results showed significantly higher histamine and tryptase levels in the allergy group, with established thresholds that could help distinguish allergic reactions from other conditions, which is important for understanding causes of death during anesthesia.
The aim of the present study was to determine the intrathecal bioavailability of a mixture of lidocaine and bupivacaine in a rabbit model of spinal anesthesia by using the microdialysis technique. Catheter and microdialysis probe were inserted under control of the view either in the epidural or in the intrathecal space. First, the epidural disposition of the mixture of bupivacaine and lidocaine was studied after epidural administration.
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