Publications by authors named "J-M Lavergne"
Background: Sleep-disordered breathing (SDB) is a common comorbidity in patients with heart failure (HF) and is associated with worse prognosis.
Objectives: This study evaluated the effects of adaptive servo-ventilation (ASV) on morbidity and mortality in a large heterogeneous population of HF patients with different etiologies/phenotypes.
Methods: Consecutive HF patients with predominant central sleep apnea (± obstructive sleep apnea) indicated for ASV were included; the control group included patients who refused or stopped ASV before three months follow-up.
Article Synopsis
- The study investigates how advanced glycation end products (AGEs) and their receptor (RAGE) influence wound healing in human corneal epithelial cells.
- AGEs significantly enhance wound healing by promoting cell migration through the activation of the NF-κB signaling pathway, but HMGB1 does not have the same effect.
- The findings indicate that the AGEs/RAGE interaction is crucial for early-stage wound healing, as evidenced by increased levels of connexin 43, a key gene involved in the process.