Context: Collagen accumulation around adipocytes and vessels (ie, pericellular fibrosis) is a hallmark of obese adipose tissue associated with altered metabolism.
Objective: Our objective was to evaluate components of basement membrane (BM) in adipose tissue, including collagen IV, a major BM component, and its relationships with metabolic parameters and TGFβ isoforms.
Design And Setting: We used immuno-techniques and gene expression approaches to detect BM components in subcutaneous and visceral adipose tissue samples.
Context: Adipocyte volume has been associated with insulin resistance and type 2 diabetes.
Objective: Our purpose was to identify an adipocyte volume threshold linked with increased insulin resistance risk, and to examine its association with insulin resistance improvement after bariatric surgery.
Setting And Design: We investigated two cohorts of Caucasian women, candidates for bariatric surgery, from two institutional centers in France (age 42.
Context: Liver and white adipose tissue (WAT) develop inflammation and fibrosis.
Objective: The aim of the study was to evaluate the bioclinical relevance of WAT fibrosis in morbid obesity and diabetes and the relationships with tissue stiffness measured using a novel device.
Design And Setting: Observational and longitudinal studies were conducted in a hospital nutrition department.
Aim Of The Study: The aim of this retrospective multicenter study was to evaluate the feasibility and the results of laparoscopic resection of benign submucosal gastric tumors.
Patients And Methods: We reviewed the cases of 65 patients (20 centers) who have been operated on laparoscopically for benign submucosal gastric tumors. The tumor was symptomatic in 56 cases, located on the posterior wall in 23 cases.