Publications by authors named "J-K Jameson"
Article Synopsis
- Patients with transposition of the great arteries (TGA) and systemic right ventricle face serious heart-related risks, and researchers sought to determine if specific invasive hemodynamic measures can predict outcomes.
- The study included 242 adults who underwent cardiac catheterization from 1994 to 2020, analyzing various hemodynamic parameters over an average follow-up period of 11.4 years.
- Results indicated that a low aortic pulsatility index (<1.5) strongly predicts negative outcomes such as death or the need for heart transplantation, with the cold/wet hemodynamic profile presenting the highest associated risk.
Background: Electrical conduction from the cardiac sinoatrial node to the ventricles is critical for normal heart function. Genome-wide association studies have identified more than a dozen common genetic loci that are associated with PR interval. However, it is unclear whether rare and low-frequency variants also contribute to PR interval heritability.
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