Publications by authors named "J-F Tolsa"

An adequate mineral supply to preterm infants is essential for normal growth and development. This study aimed to compare the mineral contents of human milk (HM) from healthy mothers of preterm (28-32 weeks) and full term (>37 weeks) infants. Samples were collected weekly for eight weeks for the term group ( = 34) and, biweekly up to 16 weeks for the preterm group ( = 27).

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Background: Mother's own milk is the optimal source of nutrients and provides numerous health advantages for mothers and infants. As they have supplementary nutritional needs, very preterm infants may require fortification of human milk (HM). Addressing HM composition and variations is essential to optimize HM fortification strategies for these vulnerable infants.

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Article Synopsis
  • Human milk oligosaccharides (HMOs) are essential in human milk for protecting infants from infections, especially benefiting vulnerable preterm infants when fed human milk.
  • This study analyzed the HMO composition in milk samples from mothers of very preterm and term infants to see if there were differences based on lactation stage and infant age.
  • The findings showed that while most HMO concentrations were similar at equivalent postpartum ages, preterm milk had lower levels of certain fucosylated HMOs and higher levels of some sialylated oligosaccharides, particularly around 40 weeks of postmenstrual age, indicating potential clinical significance.
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We longitudinally compared fatty acids (FA) from human milk (HM) of mothers delivering term and preterm infants. HM was collected for 4 months postpartum at 12 time points for preterm and for 2 months postpartum at 8 time points for term group. Samples were collected from the first feed of the morning, and single breast was fully expressed.

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