Publications by authors named "J-D Laredo"

Background: Precise lower limb measurements are crucial for assessing musculoskeletal health; fully automated solutions have the potential to enhance standardization and reproducibility of these measurements. This study compared the measurements performed by BoneMetrics (Gleamer, Paris, France), a commercial artificial intelligence (AI)-based software, to expert manual measurements on anteroposterior full-leg standing radiographs.

Methods: A retrospective analysis was conducted on a dataset comprising consecutive anteroposterior full-leg standing radiographs obtained from four imaging institutions.

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Objective: To develop and validate an enthesitis magnetic resonance imaging (MRI) scoring system for spondyloarthritis/psoriatic arthritis, using the heel as model.

Methods: Consensus definitions of key pathologies and 3 heel enthesitis multireader scoring exercises were done, separated by discussion, training, and calibration.

Results: Definitions for bone and soft tissue pathologies were agreed.

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Purpose To evaluate determinants of hip fracture by assessing soft-tissue composition of the upper thigh at CT. Materials and Methods In this retrospective analysis of prospectively collected data, CT studies in 55 female control participants (mean age, 73.1 years ± 9.

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Case: A 48-year-old woman was unable to walk due to an extensive osteolytic supra-acetabular iliac wing metastatic lymphoma involving the arcuate line. A minimally invasive technique that combined percutaneous nailing of the iliac bone with a customized nail and cementoplasty (intraosseous injection of polymethylmethacrylate) was performed. At the 1-year follow-up, she was able to walk without crutches, and computed tomography (CT) showed a stable iliac bone fixation.

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Article Synopsis
  • The study aimed to compare the effectiveness of three imaging techniques (radiography, DXA, and quantitative CT) and finite element modeling (FEM) in predicting the failure load of the proximal femur.
  • A total of 40 pairs of cadaver femurs from older individuals were used to gather data on geometric and densitometric parameters, which were then analyzed through various statistical methods to assess predictive capabilities.
  • Results showed that DXA provided the strongest correlation with mechanical failure load, particularly with total and trochanteric bone mineral density, while radiography and quantitative CT also showed significant predictive values.
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Purpose To determine the in vivo effects of several particulate steroids on microvascular perfusion by using intravital microscopy in a mice model and to investigate the in vitro interactions between these particulate steroids and red blood cells (RBCs). Materials and Methods The study was conducted in agreement with the guidelines of the National Committee of Ethic Reflection on Animal Experimentation. By using intravital microscopy of mouse cremaster muscle, the in vivo effects of several particulate steroids on microvascular perfusion were assessed.

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