Publications by authors named "J-C Rueckert"

Article Synopsis
  • Surgical resection is the primary treatment for patients with large or symptomatic brain metastases, but there's still a risk of local failure, prompting the development of a prediction tool to identify those at high risk.
  • Data from the AURORA study included 253 patients for training and 99 for external testing, utilizing radiomic features from MRI scans to enhance prediction accuracy.
  • The elastic net regression model combining radiomic and clinical features showed a significant improvement in predicting local failure, with lower risk groups experiencing only 9% failure at 24 months compared to 74% in high-risk groups, suggesting potential for improved patient follow-up and treatment.
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While musculoskeletal imaging volumes are increasing, there is a relative shortage of subspecialized musculoskeletal radiologists to interpret the studies. Will artificial intelligence (AI) be the solution? For AI to be the solution, the wide implementation of AI-supported data acquisition methods in clinical practice requires establishing trusted and reliable results. This implementation will demand close collaboration between core AI researchers and clinical radiologists.

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Background: The effectiveness of endovascular therapy in patients with stroke caused by basilar-artery occlusion has not been well studied.

Methods: We randomly assigned patients within 6 hours after the estimated time of onset of a stroke due to basilar-artery occlusion, in a 1:1 ratio, to receive endovascular therapy or standard medical care. The primary outcome was a favorable functional outcome, defined as a score of 0 to 3 on the modified Rankin scale (range, 0 to 6, with 0 indicating no disability, 3 indicating moderate disability, and 6 indicating death) at 90 days.

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