Publications by authors named "J-C Dalphin"

Introduction: Interstitial lung diseases (ILDs) can be caused by mutations in the and genes, which encode the surfactant protein (SP) complex SP-A. Only 11 or mutations have so far been reported worldwide, of which five have been functionally assessed. In the framework of ILD molecular diagnosis, we identified 14 independent patients with pathogenic or mutations.

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Article Synopsis
  • The study investigates comorbidities in patients with COPD, focusing on those exposed to organic dust (like dairy farmers) and tobacco smoking.
  • The research finds that, regardless of exposure, patients with COPD do not have a higher frequency of cardiovascular issues compared to non-COPD individuals.
  • Tobacco smoking is linked to an increased risk of cardiovascular comorbidities, while exposure to organic dust appears to lower that risk, emphasizing the importance of managing cardiovascular health in COPD patients.
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Copd: think about occupational exposures! Unfortunately, the occupational exposures of COPD are still poorly taught and poorly researched, although they account for 15 to 20% of all COPD. The clinician must know them well and therefore systematically seek them for any newly diagnosed case. A thorough and rigorous professional interview allows to trace the entire professional career, even when the patient smokes.

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