Childhood abuse neglect and risk for major psychiatric disorders.

Background: Childhood maltreatment (CM) is a strong risk factor for psychiatric disorders but serves in its current definitions as an umbrella for various fundamentally different childhood experiences. As first step toward a more refined analysis of the impact of CM, our objective is to revisit the relation of abuse and neglect, major subtypes of CM, with symptoms across disorders.

Methods: Three longitudinal studies of major depressive disorder (MDD, = 1240), bipolar disorder (BD, = 1339), and schizophrenia (SCZ, = 577), each including controls ( = 881), were analyzed.

A systematic review of biological, social and environmental factors associated with epigenetic clock acceleration.

Aging involves a diverse set of biological changes accumulating over time that leads to increased risk of morbidity and mortality. Epigenetic clocks are now widely used to quantify biological aging, in order to investigate determinants that modify the rate of aging and to predict age-related outcomes. Numerous biological, social and environmental factors have been investigated for their relationship to epigenetic clock acceleration and deceleration.

Association between polysomnographic parameters of sleep bruxism and attrition-type tooth wear.

Background: Clinically, sleep bruxism is considered to be associated with the presence of tooth wear, but strong evidence is still lacking.

Objective: To examine whether an association exists between polysomnographic parameters, recorded from patients with possible sleep bruxism and tooth wear.

Methods: Sixty-three possible sleep bruxers (19 males and 44 females, mean ± SD age = 38.

Do sleep hygiene measures and progressive muscle relaxation influence sleep bruxism? Report of a randomised controlled trial.

The aim of this study was to assess the effects of sleep hygiene measures combined with relaxation techniques in the management of sleep bruxism (SB) in a double-blind, parallel, controlled, randomised clinical trial design. Sixteen participants (mean ± s.d.

Time-linked concurrence of sleep bruxism, periodic limb movements, and EEG arousals in sleep bruxers and healthy controls.

Objective: Sleep bruxism (SB) and periodic limb movements during sleep (PLMS) may have a common underlying neurophysiologic mechanism, especially in relation to the occurrence of sleep-related electroencephalographic (EEG) arousals. To test this hypothesis, three research questions were assessed. First, it was assessed whether PLMS events occur more frequently in SB patients than in individuals without SB.