Publications by authors named "J van der Kemp"

Controlling biomolecular condensate formation within the nucleus is critical for genome function. In this issue, Xu et al. (https://doi.

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During the 2016-2017 Canada Basin Acoustic Propagation Experiment, an ocean acoustic tomography array with a radius of 150 km measured the impulse responses of the ocean every 4 hr at a variety of ranges and bearings using broadband signals with center frequencies from 172.5 to 275 Hz. Ice-profiling sonar data showed a gradual increase in ice draft over the winter with daily median ice drafts reaching maxima of about 1.

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Background: General practitioners (GPs) play a key role in managing osteoarthritis, including referring to appropriate management services. Physiotherapist-led osteoarthritis management programs and advanced practice triage services are effective, but GPs views on them are largely unknown. This study aimed to explore general practitioner perspectives on: (1) managing patients with hip and knee osteoarthritis, and (2) physiotherapy-led osteoarthritis care and referral pathways.

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Article Synopsis
  • The study explores the link between hip shape and the risk of hip osteoarthritis and fractures, using data from large cohorts to analyze genetic factors influencing hip shape.
  • Researchers identified numerous genetic signals related to hip shape but found no causal effect of hip shape on osteoarthritis, while certain hip shapes were linked to a higher risk of hip fractures.
  • The findings suggest that focusing on hip shape might not be an effective strategy for preventing osteoarthritis in older adults, despite its association with hip fractures.
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Article Synopsis
  • - Patients with chronic kidney disease (CKD) have elevated levels of trimethylamine N-oxide (TMAO), a harmful substance linked to heart disease, and the study explores how gut microbes, specifically methanogenic archaea, might help reduce TMAO by consuming its precursor, trimethylamine (TMA).
  • - The study involved 25 CKD patients, where TMAO levels were measured and gut microbial DNA was sequenced, revealing high TMAO levels and a connection to archaea, particularly a significant negative correlation with the genus Methanobrevibacter.
  • - This research is pioneering in linking TMAO levels with archaea in CKD patients, highlighting the potential role of specific
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