Publications by authors named "J van de Nes"
Neuroblastoma is a childhood developmental cancer; however, its embryonic origins remain poorly understood. Moreover, in-depth studies of early tumor-driving events are limited because of the lack of appropriate models. Herein, we analyzed RNA sequencing data obtained from human neuroblastoma samples and found that loss of expression of trunk neural crest-enriched gene associates with advanced disease and worse outcome.
View Article and Find Full Text PDFBackground: Evidence for effectiveness of radiotherapy for Ledderhose disease was demonstrated in the LedRad-study. However, the health economic impact of Ledderhose disease is unclear. Therefore, an economic evaluation alongside the LedRad-study was planned.
View Article and Find Full Text PDFArticle Synopsis
- * The trial included 84 patients and found that those receiving radiotherapy experienced significant pain reduction and improvements in quality of life and walking abilities at 12 and 18 months compared to those who received a placebo.
- * Most side effects reported were mild, with 87% resolving by the 18-month follow-up, reinforcing radiotherapy's effectiveness for this condition.
Objective: The authors investigated tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) and influenza vaccination during pregnancy following Advisory Committee on Immunization Practices' (ACIP's) recommendation for antenatal pertussis vaccination.
Methods: A retrospective chart review was performed in 2019 of women receiving prenatal care at our institution between January 1, 2014 and December 31, 2018. Receipt of ACIP-recommended vaccines were examined using Current Procedural Terminology codes to identify initiation of prenatal care, then administration of Tdap and influenza vaccines.
Article Synopsis
- A study was conducted to investigate how walking affects plantar pressure distribution in patients with painful Ledderhose disease compared to people without foot issues.
- Researchers collected pedobarography data from 41 affected patients and 41 healthy controls, focusing on various foot sections to assess peak pressure and force distribution.
- Results showed that patients experienced increased pressure in areas like the heel and toes, while pressure was reduced in the midfoot regions, indicating a pressure shift during walking to avoid pain.