Optimization of Neuroprosthetic Vision via End-to-End Deep Reinforcement Learning.

Visual neuroprostheses are a promising approach to restore basic sight in visually impaired people. A major challenge is to condense the sensory information contained in a complex environment into meaningful stimulation patterns at low spatial and temporal resolution. Previous approaches considered task-agnostic feature extractors such as edge detectors or semantic segmentation, which are likely suboptimal for specific tasks in complex dynamic environments.

[Sunburn of a reconstructed breast: risk of denervated tissue].

More and more women opt for breast reconstruction with autologous tissue after breast removal. Reconstruction with a deep inferior epigastric perforator (DIEP) flap is the most common technique. In this operation, the nerves of the DIEP flap are cut.

The effect of photodynamic treatment of yeast with the sensitizer chloroaluminum phthalocyanine on various cellular parameters.

Photodynamic treatment of Kluyveromyces marxianus with chloroaluminum-phthalocyanine resulted in loss of clonogenicity. Several parameters were studied to identify targets that could be related to loss of colony-forming capacity. Inhibition of various plasma membrane-bound processes was observed, such as substrate transport and plasma membrane ATPase activity.

The effect of protoporphyrin on the susceptibility of human erythrocytes to oxidative stress: exposure to hydrogen peroxide.

Binding of protoporphyrin caused a perturbation of the erythrocyte membrane, as reflected by a change in cell shape from discoid to echinocyte, and a concomitant increase in mean cellular volume and K(+)-loss. Protoporphyrin-induced changes could be prevented by the presence of BaCl2, whereas binding of protoporphyrin was not affected. Exposure of erythrocytes to hydrogen peroxide leads to K(+)-leakage and lipid peroxidation.