Publications by authors named "J intHout"
The aim of this study is to validate a uniform method for measuring perineal descent which can be used for different imaging methods, to establish cut-off values for this measurement, and to assess diagnostic test accuracy (DTA) of imaging techniques using these cut-off values. Secondly, the study aims to correlate perineal descent to symptoms, signs and imaging findings in women with obstructed defaecation syndrome (ODS) to assess its clinical relevance. Cross-sectional study of 131 women with symptoms of ODS.
View Article and Find Full Text PDFObjective: To compare menopause-related quality of life (QoL) after risk-reducing salpingectomy (RRS) versus risk-reducing salpingo-oophorectomy (RRSO) until 3 years of post-surgery.
Design: A prospective study (TUBA study) with treatment allocation based on patients' preference. Data were collected pre-surgery and at 3 months, 1 and 3 years of post-surgery.
Antipsychotic Polypharmacy in Time Course: Evidence for a Cross-titration Trap.
J Clin Psychopharmacol
January 2025
Purpose/background: Antipsychotic polypharmacy (APP) is controversial yet applied in 20% of patients with psychotic disorders. We investigated indications for initiating and continuing APP, including the contribution of unfinished cross-titrations.
Methods/procedures: This 2-month study was part of a prospective study to reduce inappropriate APP in inpatients.
Article Synopsis
- There is growing support for remote speech therapy as a beneficial treatment for improving speech quality and quality of life in patients with Parkinson's disease.
- The PERSPECTIVE study found that after 8 weeks, patients receiving remote therapy reported better communication and a more significant reduction in disease-related quality of life issues compared to those on a waiting list.
- The results suggest that personalized remote speech therapy can have a positive impact, warranting further exploration and potential integration into standard care for Parkinson’s disease.
Article Synopsis
- Lymph node metastases are important for understanding colorectal cancer, and the study looks at how two features, extranodal extension and tumor deposits, affect patient outcomes.
- The research included 20 studies with over 7,700 cases to compare how these two features relate to survival after treatment.
- Results suggest that having tumor deposits usually leads to worse survival rates compared to having extranodal extension, but further studies are needed to confirm these findings.