Publications by authors named "J den Arend"
Background: ALPPS leads to fast and effective liver hypertrophy. This enables the resection of extended tumors. Conventional ALPPS is associated with high morbidity and mortality.
View Article and Find Full Text PDFSound localization testing is key for comprehensive hearing evaluations, particularly in cases of suspected auditory processing disorders. However, sound localization is not commonly assessed in clinical practice, likely due to the complexity and size of conventional measurement systems, which require semicircular loudspeaker arrays in large and acoustically treated rooms. To address this issue, we investigated the feasibility of testing sound localization in virtual reality (VR).
View Article and Find Full Text PDFHuman voice directivity shows horizontal asymmetries caused by the shape of the lips or the position of the tooth and tongue during vocalization. This study presents and analyzes the asymmetries of voice directivity datasets of 23 different phonemes. The asymmetries were determined from datasets obtained in previous measurements with 13 subjects in a surrounding spherical microphone array.
View Article and Find Full Text PDFArticle Synopsis
- Sepsis is a serious condition that can lead to acute kidney injury (AKI), but a new treatment, ilofotase alfa, shows promise in improving kidney function and reducing mortality in patients with sepsis-associated AKI.
- A phase 3 clinical trial is being conducted to further confirm the benefits of ilofotase alfa by comparing it to a placebo, involving around 1,400 participants across multiple countries.
- The trial adheres to strict ethical guidelines and will include interim evaluations to ensure safety and effectiveness, with the potential to stop early if needed.