Experiences with telemedicine for HIV care in two federally qualified health centers in Los Angeles: a qualitative study.

Background: The SARS-CoV-2 pandemic has resulted in an increase in telemedicine utilization for routine HIV care. However, there is limited information on perceptions of and experiences with telemedicine from United States (U.S.

Long-Term Efficacy, Safety, and Durability of Cabotegravir and Rilpivirine as 2-Drug Oral Maintenance Therapy After 6 Years of Study.

Background: In the LATTE study, daily oral cabotegravir + rilpivirine demonstrated higher rates of efficacy than efavirenz + 2 nucleoside reverse-transcriptase inhibitors (NRTIs) through Week 96 in antiretroviral therapy (ART)-naive adults with human immunodeficiency virus (HIV)-1. We present the results from 6 years of continued treatment with oral cabotegravir + rilpivirine.

Methods: LATTE was a phase IIb, randomized, multicenter, partially blinded, dose-ranging study in ART-naive adults with HIV-1.

Long-acting cabotegravir and rilpivirine for HIV-1 suppression: switch to 2-monthly dosing after 5 years of daily oral therapy.

Objectives: Long-acting formulations of cabotegravir (CAB) and rilpivirine (RPV) have demonstrated efficacy in Phase 3 studies. POLAR (NCT03639311) assessed antiviral activity and safety of CAB+RPV long-acting administered every 2 months (Q2M) in adults living with HIV-1 who previously received daily oral CAB+RPV in LATTE (NCT01641809).

Design: A Phase 2b, multicenter, open-label, rollover study.

Experimental validation of pressure swing regeneration for faster cycling in sorption enhanced dimethyl ether synthesis.

Sorption enhanced dimethyl ether synthesis (SEDMES) is a novel DME production route from CO-rich feedstocks. In situ water removal by adsorption results in high single-pass conversions, thereby circumventing the disadvantages of conventional routes, such as low carbon efficiency, energy intensive downstream separation and large recycling. The first-time demonstration of pressure swing regeneration with 80% single-pass carbon selectivity to DME allows for an enormous increase in productivity.

Assessing the effectiveness of Sustainable Land Management for large-scale climate change adaptation.

Climate change will strongly affect essential ecosystem services, like the provision of freshwater, food production, soil erosion and flood control. Sustainable Land Management (SLM) practices are increasingly promoted to contribute to climate change mitigation and adaptation, but there is lack of evidence at scales most relevant for policymaking. We evaluated the effectiveness of SLM in a large Mediterranean catchment where climate change is projected to significantly reduce water security.