Publications by authors named "J de Jonge"
Background: Donor livers from older donation after circulatory death (DCD) donors are frequently discarded for transplantation because of the high risk of graft failure. It is unknown whether DCD livers from older donors benefit from dynamic preservation.
Methods: In a multicenter study, we retrospectively compared graft and patient outcomes after transplantation of livers from DCD donors older than 60 y, preserved with either static cold storage (SCS), ex situ sequential dual hypothermic perfusion, controlled oxygenated rewarming, and normothermic perfusion (DHOPE-COR-NMP), or in situ abdominal normothermic regional perfusion (aNRP).
Liver transplantation is associated with a high risk of postoperative complications due to the complexity of the surgical procedure, recipient disease severity and wide range of graft quality which remains somewhat unpredictable. However, survival rates after transplantation continue to improve and the focus has thus turned to other clinically relevant endpoints including posttransplant complications, patient quality of life and costs. Procedures like liver transplantation offer the entire spectrum of postsurgical events, even in donor-recipient constellations deemed of low risk within recently defined benchmark criteria.
View Article and Find Full Text PDFAim: This study examines the moderating role of specific job resources in the association between job demands, vigour, sustainable performance and fatigue in nursing home staff.
Design: A multi-location cross-sectional survey study in line with the STROBE guidelines.
Methods: Online self-completion questionnaires were distributed in the Summer of 2022.
Article Synopsis
- Research investigates the cost-effectiveness of dual hypothermic oxygenated machine perfusion (DHOPE) in liver transplantation, especially after circulatory death (DCD), compared to traditional static cold storage (SCS).
- A multicenter trial with 119 patients found that the average cost for DHOPE was €110,794, whereas SCS costs averaged €126,221, with significant savings in intensive care and other nonsurgical interventions.
- DHOPE proved to be cost-effective after just one procedure in certain scenarios, while scenarios that included additional costs for personnel and facilities became cost-effective after 25-30 procedures.