State-wise variation and inequalities in caesarean delivery rates in India: analysis of the National Family Health Survey-5 (2019-2021) data.

Background: India's caesarean delivery (CD) rate of 21.5% suggests adequate national access to CD but may mask significant disparities. We examined variation in CD rates across states (geography), wealth, and health care sector (public versus private).

Plasma transfusion in the intensive care unit.

Background: Current guidelines discourage prophylactic plasma use in non-bleeding patients. This study assesses global plasma transfusion practices in the intensive care unit (ICU) and their alignment with current guidelines.

Study Design And Methods: This was a sub-study of an international, prospective, observational cohort.

Increased sea level rise accelerates carbon sequestration in a macro-tidal salt marsh.

Salt marshes are known as key ecosystems for nature-based climate mitigation through organic carbon sequestration into their sediment beds, but at the same time they are affected by accelerating sea level rise induced by climate warming. Consequently, an important question is how organic carbon accumulation rates (OCAR) of salt marshes will respond to future accelerating rates of relative sea level rise (RSLR). To date, existing insights are either based on (1) comparison of geographically distant marsh sites, differing in local RSLR rates but also in other environmental conditions that additionally can affect OCAR, or (2) experiments in given marsh sites, in which proxies for RSLR are manipulated, but run over periods of years instead of decades, the latter being the relevant time scale of marsh responses to RSLR.

Endothelial Protection and Improved Micro- and Macrocirculation with Hemoadsorption in Critically Ill Patients.

A dysregulated immune response is associated with an excessive release of cytokines that can lead to systemic vasoplegia and vasoplegic shock with the development of multiorgan failure that is associated with an increased risk of dying. Under physiological circumstances, the endothelium and the glycocalyx are responsible for maintaining vascular tone, capillary permeability, and hemostasis, and controlling inflammation. In hyperinflammation, the endothelium and glycocalyx become damaged due to the excessive production of certain toxic proteins, along with an overwhelming release of cytokines.