Parallel detection and spatial mapping of large nuclear spin clusters.

Nuclear magnetic resonance imaging (MRI) at the atomic scale offers exciting prospects for determining the structure and function of individual molecules and proteins. Quantum defects in diamond have recently emerged as a promising platform towards reaching this goal, and allowed for the detection and localization of single nuclear spins under ambient conditions. Here, we present an efficient strategy for extending imaging to large nuclear spin clusters, fulfilling an important requirement towards a single-molecule MRI technique.

Multi-Modal Segmentation of 3D Brain Scans Using Neural Networks.

Anatomical segmentation of brain scans is highly relevant for diagnostics and neuroradiology research. Conventionally, segmentation is performed on -weighted MRI scans, due to the strong soft-tissue contrast. In this work, we report on a comparative study of automated, learning-based brain segmentation on various other contrasts of MRI and also computed tomography (CT) scans and investigate the anatomical soft-tissue information contained in these imaging modalities.

Broadband radio-frequency transmitter for fast nuclear spin control.

The active manipulation of nuclear spins with radio-frequency (RF) coils is at the heart of nuclear magnetic resonance (NMR) spectroscopy and spin-based quantum devices. Here, we present a miniature RF transmitter designed to generate strong RF pulses over a broad bandwidth, allowing for fast spin rotations on arbitrary nuclear species. Our design incorporates (i) a planar multilayer geometry that generates a large field of 4.

Tracking the precession of single nuclear spins by weak measurements.

Nuclear magnetic resonance (NMR) spectroscopy is a powerful technique for analysing the structure and function of molecules, and for performing three-dimensional imaging of their spin densities. At the heart of NMR spectrometers is the detection of electromagnetic radiation, in the form of a free induction decay signal, generated by nuclei precessing around an applied magnetic field. Whereas conventional NMR requires signals from 10 or more nuclei, recent advances in sensitive magnetometry have dramatically lowered the required number of nuclei to a level where a few or even individual nuclear spins can be detected.

Three-Dimensional Nuclear Spin Positioning Using Coherent Radio-Frequency Control.

Distance measurements via the dipolar interaction are fundamental to the application of nuclear magnetic resonance (NMR) to molecular structure determination, but they provide information on only the absolute distance r and polar angle θ between spins. In this Letter, we present a protocol to also retrieve the azimuth angle ϕ. Our method relies on measuring the nuclear precession phase after the application of a control pulse with a calibrated external radio-frequency coil.