Publications by authors named "J Zone"
There is a reported association between oral contact allergy and oral lichen planus (OLP). Likewise oral squamous cell carcinoma (oSCC) is associated with OLP. It is hypothesized that chronic inflammation may contribute to oSCC risk.
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- Dermatitis herpetiformis (DH) is a rare skin condition triggered by gluten, characterized by the presence of specific IgA autoantibodies against proteins like endomysium and transglutaminase.
- An international study analyzed serum samples from 242 DH patients at diagnosis, using various methods including indirect immunofluorescence on monkey oesophagus and ELISA tests for specific autoantibodies.
- The findings showed that IgA antibodies detected via indirect immunofluorescence had the highest reactivity and diagnostic accuracy, indicating a strong link between these autoantibodies and DH, which can be further improved with additional testing.
Article Synopsis
- * Conducted at the University of Utah Health, researchers analyzed Skindex-16 scores from 192 patients diagnosed with various AIBD subtypes between 2016 and 2020, assessing disease severity and patient-reported flare status.
- * Results showed that flare state scores were notably higher, indicating a greater negative effect on skin-related quality of life, and the study also evaluated how well Skindex-16 correlated with medical and patient-reported outcomes.