Publications by authors named "J Zoll"
Article Synopsis
- Obesity, type 2 diabetes, and nonalcoholic fatty liver disease (NAFLD) are significant public health issues, with high sugar and carbohydrate intake being debated as major contributors to these conditions.
- * A study was conducted on male mice comparing the effects of a low-carbohydrate high-fat diet (LCHFD) and a high-fat high-sugar Western diet (WD) on obesity and related health issues.
- * Results indicated that the LCHFD effectively prevented weight gain and maintained normal glucose levels while the WD led to obesity, glucose intolerance, and NAFLD, highlighting the potential benefits of LCHFD for managing these metabolic complications.
Weight cycling is a major challenge in obesity management. Caloric restriction is known to promote this phenomenon, but the impact of macronutrient changes during dieting remains unclear. This study aimed to determine the role of macronutrient changes in weight maintenance without caloric restriction by alternating between two hypercaloric diets: a high-carbohydrate, high-fat Western diet (WD) and a low-carbohydrate, high-fat diet (LCHDF).
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- Physiological calcification in soft tissues is linked to aging and certain genetic disorders, particularly involving ABCC6 gene variations that lead to pseudoxanthoma elasticum (PXE) and other forms of arterial calcification.
- Research indicates that inflammation plays a significant role in the calcification process in PXE, moving attention from the liver's involvement to the contributions of peripheral tissues.
- The study found that bone marrow-derived ABCC6 influences calcification, as restoring normal bone marrow in Abcc6 mice significantly reduced mineralization, highlighting the importance of the immune system and inflammation in these conditions.
[Beneficial effects of ketogenic diet for Alzheimer's disease management].
Biol Aujourdhui
November 2023
Alzheimer's disease (AD) is a neurodegenerative disease that affects almost 1 million people in France and 55 million in the world. This pathology is a global health preoccupation because of the lack of efficient curative treatment and the increase of its prevalence. During the last decade, the comprehension of pathophysiological mechanisms involved in AD have been improved.
View Article and Find Full Text PDFThe opportunistic pathogen is found on all continents and thrives in soil and agricultural environments. Its ability to readily adapt to novel environments and to produce billions of spores led to the spread of azole-resistant across the globe, posing a threat to many immunocompromised patients, including critically ill patients with severe influenza or COVID-19. In our study, we sought to compare the adaptational response to azoles from isolates that differ in azole susceptibility and genetic background.
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