Synopsis of recent research by authors named "J Zico Kolter"
- J Zico Kolter's recent research primarily focuses on the roles of macrophages in various physiological and pathological contexts, including their behavior in the dermal microenvironment during skin infections and systemic immune challenges.
- His work highlights the intricate metabolic and signaling pathways that modulate macrophage functions in response to infections, emphasizing their adaptation to both homeostatic and inflammatory cues, and the epigenetic impacts of early immune challenges on behavior and cognition in males versus females.
- Kolter also explores therapeutic strategies, such as the use of human β-defensin 2 to mitigate conditions like acute graft-versus-host disease, revealing the potential of endogenous peptides in regulating immune responses and promoting tissue healing.
