Support by telestroke networks is associated with increased intravenous thrombolysis and reduced hospital transfers: A german claims data analysis.

Background: Acute stroke treatment is time-critical. To provide qualified stroke care in areas without 24/7 availability of a stroke neurologist, the concept of teleneurology was established, which is based on remote video communication through telemedicine organized by telestroke networks. Data on the effectiveness and efficiency of stroke treatment via teleneurology is very scarce and is therefore partly questioned in the healthcare sector.

Towards large-scale analyses of settlement patterns in urbanizing landscapes-findings of first studies for India, Egypt, and China.

Improved ability to assess and categorize the spatial characteristics of settlement patterns is required for a deeper understanding of how urbanization is driving land use and land cover transformation and its effects. Two approaches to the globally available settlement maps of the World Settlement Footprint 3D support a detailed assessment of spatial characteristics of settlement patterns in rural to urban landscapes and across scales: graph-based spatial network analysis and elements of fractal theory. Based on first comprehensive tests for the Punjab (India), the Nile Delta (Egypt) and the North China Plain, the results of our study suggest that the presented methods allow a quantitative and qualitative characterization and comparison of settlement patterns between different regions of the world.

Medical Costs of Patients Undergoing Esophageal Atresia Repair are Mainly Influenced by Associated Malformations.

Background:  Esophageal atresia (EA) is a rare disease requiring surgical repair, usually within the first days of life. Patients with EA require intensive postoperative care and often have comorbidities. There is a lack of data on the costs incurred by patients with EA during the first year of life.

[Rheumatological care in Germany : Memorandum of the German Society for Rheumatology and Clinical Immunology 2024].

Background: Rheumatology in Germany is facing major challenges. The need for rheumatological care is increasing and can no longer be met in some regions for capacity reasons. Too many people with an inflammatory rheumatic disease (IRD) have to forego appropriate care or receive it too late.

Galactose-1-phosphate inhibits cytochrome c oxidase and causes mitochondrial dysfunction in classic galactosemia.

Classic galactosemia is an inborn error of metabolism caused by mutations in the GALT gene resulting in the diminished activity of the galactose-1-phosphate uridyltransferase enzyme. This reduced GALT activity leads to the buildup of the toxic intermediate galactose-1-phosphate and a decrease in ATP levels upon exposure to galactose. In this work, we focused our attention on mitochondrial oxidative phosphorylation in the context of this metabolic disorder.