Publications by authors named "J Zdolsek"

Intravenous volume loading is a common treatment when hypovolemia is a potential cause of oliguria. We studied whether the effectiveness of Ringer's solution and 20% albumin in inducing diuresis differs depending on the mean arterial pressure (MAP). For this purpose, volume kinetic analysis was performed based on urine output and hemoglobin-derived plasma dilution obtained during and after 136 infusions of Ringer and 85 infusions of 20% albumin.

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Background: The latissimus dorsi (LD) flap is a commonly used method for breast reconstruction after mastectomy. In this study, we present a long-term follow-up and effects of refining surgery on patient satisfaction and quality of life after breast reconstruction with the extended LD flap, using the BREAST-Q questionnaire.

Objectives: The aim of this study was to investigate the patient-reported long-term results after breast reconstruction with the extended LD myocutaneous flap.

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Background: Intravenous infusion of hyper-oncotic 20 % albumin expands the plasma volume by approximately twice the infused volume. We investigated whether the recruited fluid stems from accelerated flow of efferent lymph, which would add protein to the plasma, or from reversed transcapillary solvent filtration, where the solvent is expected to be low in protein.

Methods: We analyzed data from 27 intravenous infusions of 20 % albumin (3 mL/kg; approximately 200 mL) over 30 min given to 27 volunteers and patients.

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Article Synopsis
  • The study investigates whether hyperchloremic metabolic acidosis in diabetic ketoacidosis treatment is due to resuscitation fluid chloride levels or altered plasma volume effects on the sodium-chloride (Na-Cl) gap.
  • The initial analysis showed that patients had a lower-than-normal plasma volume and an increased Na-Cl gap that helped counteract acidosis.
  • However, when correcting for plasma volume, a significant decrease in the Na-Cl gap was revealed, suggesting that hyperchloremic acidosis may be linked to the restoration of plasma volume rather than just chloride levels in IV fluids.
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