Publications by authors named "J Zan"
Article Synopsis
- A new test called Time-resolved fluorescence immunochromatographic test strips (TRFIS) has been created for the fast detection of a specific type of exosome related to liver cancer, targeting a protein called glypican-3 (GPC3).
- The test allows for direct detection of these exosomes in plasma without needing complex isolation methods, completing the entire process in just 15 minutes.
- Clinical testing showed that TRFIS can effectively differentiate HCC patients from healthy individuals with high sensitivity and specificity, presenting a promising tool for early liver cancer screening.
Three-phase partitioning (TPP) is promising for isolating bioactive polysaccharides, but t-butanol's environmental impact limits its application. Deep eutectic solvents can serve as a green and recyclable alternative to t-butanol. This study introduces an ultrasonic-assisted DES three-phase partitioning (UA-TPP-DES) system to extract and purify American ginseng polysaccharides (AGPs).
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- Population changes in and out of Africa have significantly shaped human evolution.
- A continental-scale study of hominin-environment interactions in Eurasia reveals how climate transitions influenced early human dispersals.
- High-resolution carbon isotope data indicates that Mid-Pleistocene climate changes created new open habitats and landscapes, prompting hominins to adapt and expand their ranges in response to environmental challenges.
Article Synopsis
- Postural instability and cognitive dysfunction are common in Parkinson's disease (PD), necessitating improved assessment methods beyond standard scales.
- High-frequency repetitive transcranial magnetic stimulation (rTMS) may enhance both motor and cognitive functions in PD patients, prompting the need for accurate monitoring of changes.
- In a study of 159 PD patients, wearable and eye-tracking devices were used to measure gait and cognitive improvements before and after rTMS treatment, which indicated significant enhancements in motor performance and cognitive measures.
Article Synopsis
- The TESTING trial found that corticosteroids reduce kidney failure risk in patients with IgA nephropathy (IgAN), but they also increase serious side effects, highlighting the need for better biomarkers.
- This study focuses on urinary soluble CD163 (u-sCD163), suggesting it correlates with treatment response and kidney health in IgAN patients receiving steroid therapy.
- The results indicate that higher u-sCD163 levels are linked to better steroid responses and that corticosteroids significantly lower u-sCD163 levels, which may reduce the risk of kidney progression.