[Avoidance of axillary lymph node dissection in breast cancer patients with metastatic sentinel node - a pilot study].

Introduction: Axillary lymph node dissection (ALND) is a standard procedure for locoregional control in metastatic sentinel lymph nodes (SN). A number of studies have provided evidence that avoiding ALND does not worsen the general prognosis.

Methods: A group of 249 female patients with sentinel lymph node biopsy was analysed retrospectively for a 3-year period.

[The molecular genetic and clinical findings in two probands with Stargardt disease].

Purpose: The aim of our study was to describe the phenotype and to perform molecular genetic investigation in two probands of Czech origin diagnosed with Stargardt disease (STGD).

Methods: Both males underwent ocular examination including assessment by high-resolution spectral domain optical coherence tomography (SD-OCT). DNA was isolated from venous blood.

Optical coherence tomography in progressive cone dystrophy.

Aim: The aim of the study was to analyse different clinical pictures in patients with progressive cone dystrophy (PCD), to compare these with the results of optical coherence tomography (OCT) and to evaluate the benefits of this method for diagnosis.

Methods: The group consisted of 16 patients (32 eyes) with PCD. All patients were examined for visual acuity, colour sense and visual field.

Fever of unknown origin: a value of (18)F-FDG-PET/CT with integrated full diagnostic isotropic CT imaging.

Aim: The aim of presented work is to evaluate the clinical value of (18)F-FDG-PET/CT in patients with fever of unknown origin (FUO) and to compare PET/CT finding with the results of the following investigation.

Material And Method: 48 patients (24 men, 24 women, mean age 57.6 years with range 15-89 years) underwent (18)F-FDG-PET/CT due to the fever of unknown origin.

(18)F-FDG-PET/CT of orofacial tumors, a value of whole-body imaging approach.

Aim: Staging of head and neck tumors is one of the most difficult tasks in imaging techniques, due to the very complicated head and neck anatomy and serious problems with the differentiation of reactive enlarged lymph nodes and lymph nodes involved with metastases. The aim of the study was to evaluate the validity of the whole-body approach in the assessment of head and neck malignancies using (18)F-FDG-PET/CT.

Materials And Methods: The analysis of a group of 1750 consecutive whole-body procedures in all indications of (18)F-FDG-PET/CT was made according to: the presence of orofacial tumors; their histology; findings concerning the spread outside head and neck region; and findings concerning the primary staging or restaging.