Background Familial cerebral cavernous alformation (CCM) is an autosomal dominant disease caused by mutations in , , or . Cases typically present with multiple lesions, strong family history, and neurological symptoms, including seizures, headaches, or other deficits. Intracranial hemorrhage (ICH) is a severe manifestation of CCM, which can lead to death or long-term neurological deficits.
View Article and Find Full Text PDFBackground: Treatment of recurrent glioblastoma (GBM) remains problematic with survival after additional therapy typically less than 12 months. We prospectively evaluated whether outcomes might be improved with resection plus permanent implantation of a novel radiation device utilizing the gamma-emitting isotope Cs-131 embedded within bioresorbable collagen tiles.
Methods: Recurrent histologic GBM were treated in a single-arm trial.
Background: In specialized neurosurgical centers, open microsurgery is routinely performed for aneurysmal subarachnoid hemorrhage (aSAH).
Objective: To compare the cost of endovascular vs microsurgical treatment for aSAH at a single quaternary center.
Methods: All patients undergoing aSAH treatment from July 1, 2014, to July 31, 2019, were retrospectively reviewed.
Background: Nationwide study results have suggested varying trends in the incidence of aneurysmal subarachnoid hemorrhage (aSAH) over time. Herein, trends over time for aSAH treated at a quaternary care center are compared with low-volume hospitals.
Methods: Cases were retrospectively reviewed for patients with aSAH treated at our institution.