Cadmium Reduces VE-Cadherin Expression in Endothelial Cells Through Activation of the Notch Signaling Pathway.

Cadmium (Cd) is a toxic heavy metal which induces vascular disorders. Previous studies suggest that Cd in the bloodstream affects vascular endothelial cells (ECs), potentially contributing to vascular-related diseases. However, the molecular mechanisms of effects of Cd on ECs remain poorly understood.

Synergistic effect of proanthocyanidins and cefquinoxime sulfate on methicillin-resistant Staphylococcus aureus.

To address the severe problem of methicillin-resistant Staphylococcus aureus (MRSA) resistance, this study identified a single component from traditional Chinese medicine that, when used in combination with existing antibiotics, enhances the therapeutic efficacy of the antimicrobial drugs. Using the micro broth dilution method and the checkerboard dilution method, susceptibility tests were conducted on ten commonly used β-lactam antibiotics against eleven strains of MRSA. It was found that cefquinome sulfate exhibits synergistic activity with PROs.

[Research advances in the mechanism of Toll-like receptor 4 mediated intestinal injury and inflammatory response in necrotizing enterocolitis].

Necrotizing enterocolitis (NEC) is an intestinal inflammatory and necrotic disease seen in premature infants, and remains the leading cause of death resulted from gastrointestinal diseases in premature infants. The specific pathogenesis of NEC is still unclear. In recent years, a lot of studies have reported that Toll-like receptor 4 (TLR4) plays a key role in the pathogenesis of NEC.

Colors of the mind: a meta-analysis of creative arts therapy as an approach for post-traumatic stress disorder intervention.

Background: In clinical practice, creative arts therapy is frequently utilized for the treatment of traumatized adults, with reports of favorable outcomes. However, the effectiveness of this intervention in post-traumatic stress disorder (PTSD) treatment has not yet been definitively established through meta-analysis. In this meta-analysis, we aim to assess the effectiveness of creative arts therapy in the management of PTSD.