Abnormal melanin synthesis within melanocytes can result in pigmentary skin disorders. Although pigmentation alterations associated with inflammation are frequently observed, the precise reason for this clinical observation is still unknown. More specifically, although many cytokines are known to be critical for inflammatory skin processes, it is unclear how they affect epidermal melanocyte function.
View Article and Find Full Text PDFMelanosome transport is regulated by major proteins, including Rab27a, Melanophilin (Mlph), and Myosin Va (Myo-Va), that form a tripartite complex. Mutation of these proteins causes melanosome aggregation around the nucleus. Among these proteins, Mlph is a linker between Rab27a and Myo-Va.
View Article and Find Full Text PDFMicroplastic pollution significantly threatens marine ecosystems, including those with unique adaptations. This study evaluates the implications of polyethylene microplastics (PE-MPs) on the hydrothermal vent crab, Xenograpsus testudinatus. Crabs were exposed to varying fluorescent green polyethylene microspheres (FGPE) concentrations for 7 days.
View Article and Find Full Text PDFPurpose: We aimed to evaluate health-related quality of life (HRQoL) in intestinal failure (IF) patients after different modes of intestinal rehabilitation.
Methods: HRQoL was assessed using the generic 36-item Short Form Survey (SF-36, ver. 2) and visual analogue scale (VAS) in 6 different areas: diet, sleep, gastrointestinal (GI) symptoms, diarrhea, musculoskeletal pain, and other symptoms.
Biosci Biotechnol Biochem
January 2025
Eumelanin, a type of skin melanin pigment, possesses the ability to absorb a wide range of wavelengths, providing protection to the skin from ultraviolet radiation. However, excessive production of eumelanin may result in hyperpigmentation. Consequently, the development of skin-brightening products that suppress eumelanin synthesis to achieve a lighter and more even skin tone is necessary.
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